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PMID Authors Title Year # Experiments
36927399 Wang L et al. Palmitoylation promotes chaperone-mediated autophagic degradation of NLRP3 to modulate inflammation. Abstract 2023 1
36879822 Xue T et al. PPT1 regulation of HSP90α depalmitoylation participates in the pathogenesis of hyperandrogenism. Abstract 2023 2
35977495 Sun Y et al. S-palmitoylation of PCSK9 induces sorafenib resistance in liver cancer by activating the PI3K/AKT pathway. Abstract 2022 0
33462194 Mejias R et al. Increased novelty-induced locomotion, sensitivity to amphetamine, and extracellular dopamine in striatum of Zdhhc15-deficient mice. Abstract 2021 0
36711022 Lemarié FL et al. Full-length huntingtin is palmitoylated at multiple sites and post-translationally myristoylated following caspase-cleavage. Abstract 2023 0
24651384 Sanders SS et al. Identification of binding sites in Huntingtin for the Huntingtin Interacting Proteins HIP14 and HIP14L. Abstract 2014 0
34390831 Lemarié FL et al. Rescue of aberrant huntingtin palmitoylation ameliorates mutant huntingtin-induced toxicity. Abstract 2021 0
36586411 Wang L et al. Palmitoylation prevents sustained inflammation by limiting NLRP3 inflammasome activation through chaperone-mediated autophagy. Abstract 2023 3
36680184 Hu D et al. ZDHHC11 Suppresses Zika Virus Infections by Palmitoylating the Envelope Protein. Abstract 2023 0
21745643 Ho GP et al. S-nitrosylation and S-palmitoylation reciprocally regulate synaptic targeting of PSD-95. Abstract 2011 0
35492028 Yang S et al. KLF10 promotes nonalcoholic steatohepatitis progression through transcriptional activation of zDHHC7. Abstract 2022 0
36548985 Komaniecki G et al. Astrocyte Elevated Gene-1 Cys75 <i>S</i>-Palmitoylation by ZDHHC6 Regulates Its Biological Activity. Abstract 2023 0
36276642 Zhou B et al. The palmitoylation of AEG-1 dynamically modulates the progression of hepatocellular carcinoma. Abstract 2022 0
34111291 Lv K et al. Depalmitoylation rewires FLT3-ITD signaling and exacerbates leukemia progression. Abstract 2021 0
36865189 Balasubramanian A et al. Palmitoylation of gasdermin D directs its membrane translocation and pore formation in pyroptosis. Abstract 2023 0
34724258 Ma Y et al. DHHC5 facilitates oligodendrocyte development by palmitoylating and activating STAT3. Abstract 2022 0
36762613 Ozkan Kucuk NE et al. Cell cycle-dependent palmitoylation of protocadherin 7 by ZDHHC5 promotes successful cytokinesis. Abstract 2023 0
33758079 Shimell JJ et al. Regulation of hippocampal excitatory synapses by the Zdhhc5 palmitoyl acyltransferase. Abstract 2021 0
35231700 G&#xf6;k C et al. Insulin-induced palmitoylation regulates the Cardiac Na<sup>+</sup>/Ca<sup>2+</sup> exchanger NCX1. Abstract 2022 0
26418268 Fuller W et al. S-palmitoylation and the regulation of NCX1. 2016 0
33739454 Sadhukhan T et al. In a mouse model of INCL reduced S-palmitoylation of cytosolic thioesterase APT1 contributes to microglia proliferation and neuroinflammation. Abstract 2021 0
36027648 Gao X et al. Palmitoylation regulates cellular distribution of and transmembrane Ca flux through TrpM7. Abstract 2022 0
34961524 Zeng XT et al. The interactions of ZDHHC5/GOLGA7 with SARS-CoV-2 spike (S) protein and their effects on S protein's subcellular localization, palmitoylation and pseudovirus entry. Abstract 2021 0
35066577 Zhou L et al. Palmitoylation restricts SQSTM1/p62-mediated autophagic degradation of NOD2 to modulate inflammation. Abstract 2022 0
36277202 Main A et al. Dynamic but discordant alterations in zDHHC5 expression and palmitoylation of its substrates in cardiac pathologies. Abstract 2022 0
31649195 Lu Y et al. Palmitoylation of NOD1 and NOD2 is required for bacterial sensing. Abstract 2019 1
35150145 Mondal A et al. Ppt1-deficiency dysregulates lysosomal Ca<sup>++</sup> homeostasis contributing to pathogenesis in a mouse model of CLN1 disease. Abstract 2022 1
34530889 Lee JW et al. KAI1(CD82) is a key molecule to control angiogenesis and switch angiogenic milieu to quiescent state. Abstract 2021 0
22902780 Greaves J et al. Palmitoylation-induced aggregation of cysteine-string protein mutants that cause neuronal ceroid lipofuscinosis. Abstract 2012 1
33037124 Locatelli C et al. Identification of key features required for efficient S-acylation and plasma membrane targeting of sprouty-2. Abstract 2020 1
35415819 Song J et al. The Palmitoylation/Depalmitoylation Cycle is Involved in the Inhibition of AMPA Receptor Trafficking Induced by Aluminum In Vitro. Abstract 2022 1
34665481 Xie F et al. Engineering Extracellular Vesicles Enriched with Palmitoylated ACE2 as COVID-19 Therapy. Abstract 2021 1
36087837 Salaun C et al. Development of a novel high-throughput screen for the identification of new inhibitors of protein S-acylation. Abstract 2022 0
34559357 Li Y et al. AKAP150 and its Palmitoylation Contributed to Pain Hypersensitivity Via Facilitating Synaptic Incorporation of GluA1-Containing AMPA Receptor in Spinal Dorsal Horn. Abstract 2021 1
34282274 Tang J et al. Cancer cells escape p53's tumor suppression through ablation of ZDHHC1-mediated p53 palmitoylation. Abstract 2021 1
34528721 Li D et al. Palmitoylation of SARS-CoV-2 S protein is critical for S-mediated syncytia formation and virus entry. Abstract 2022 1
34897408 Wu Y et al. ZDHHC19 localizes to the cell membrane of spermatids and is involved in spermatogenesis†. Abstract 2022 0
35396942 Roig SR et al. S-acylation-dependent membrane microdomain localization of the regulatory Kvβ2.1 subunit. Abstract 2022 0
34620861 Zhang Z et al. DHHC9-mediated GLUT1 S-palmitoylation promotes glioblastoma glycolysis and tumorigenesis. Abstract 2021 1
36063887 Niki Y et al. S-Palmitoylation of Tyrosinase at Cysteine<sup>500</sup> Regulates Melanogenesis. Abstract 2022 1
35813875 Tien CF et al. Glycosylation and S-palmitoylation regulate SARS-CoV-2 spike protein intracellular trafficking. Abstract 2022 1
35746795 Ma T et al. Palmitoylation Is Indispensable for Remorin to Restrict Tobacco Mosaic Virus Cell-to-Cell Movement in <i>Nicotiana benthamiana</i>. Abstract 2022 0
35732327 Kokabee M et al. Palmitoylation of the Alternative Amino Terminus of the BTK-C Isoform Controls Subcellular Distribution and Signaling. Abstract 2022 0
35727735 Chen X et al. Oct4A palmitoylation modulates tumorigenicity and stemness in human glioblastoma cells. Abstract 2022 0
35705139 Afrin S et al. Simvastatin reduces plasma membrane caveolae and caveolin-1 in uterine leiomyomas. Abstract 2022 0
35694507 Phukan H et al. Unique Posttranslational Modification Sites of Acetylation, Citrullination, Glutarylation, and Phosphorylation Are Found to Be Specific to the Proteins Partitioned in the Triton X-114 Fractions of <i>Leptospira</i>. Abstract 2022 0
35643222 Gal J et al. S-acylation regulates the membrane association and activity of Calpain-5. Abstract 2022 0
35638903 Vardar G et al. Syntaxin-1A modulates vesicle fusion in mammalian neurons via juxtamembrane domain dependent palmitoylation of its transmembrane domain. Abstract 2022 0
35606353 Zhao C et al. GSK3β palmitoylation mediated by ZDHHC4 promotes tumorigenicity of glioblastoma stem cells in temozolomide-resistant glioblastoma through the EZH2-STAT3 axis. Abstract 2022 1
35597282 Wirth A et al. Palmitoylation of the small GTPase Cdc42 by DHHC5 modulates spine formation and gene transcription. Abstract 2022 1
35477839 Gao J et al. Proteome-wide identification of palmitoylated proteins in mouse testis. 2022 2
34884899 Ziemlińska E et al. Palm Oil-Rich Diet Affects Murine Liver Proteome and <i>S</i>-Palmitoylome. 2021 2
34200797 Zaręba-Kozioł M et al. S-Palmitoylation of Synaptic Proteins as a Novel Mechanism Underlying Sex-Dependent Differences in Neuronal Plasticity. 2021 4
33782527 Ripamonti M et al. Structural and functional analysis of LIM domain-dependent recruitment of paxillin to αvβ3 integrin-positive focal adhesions. 2021 1
33848465 Pradhan AJ et al. Protein acylation by saturated very long chain fatty acids and endocytosis are involved in necroptosis. 2021 2
33636221 Miles MR et al. Global identification of S-palmitoylated proteins and detection of palmitoylating (DHHC) enzymes in heart. 2021 3
34769186 Uzbekova S et al. Protein Palmitoylation in Bovine Ovarian Follicle. 2021 1
35358180 Gorenberg EL et al. Identification of substrates of palmitoyl protein thioesterase 1 highlights roles of depalmitoylation in disulfide bond formation and synaptic function. 2022 2
33788965 Okui M et al. Posttranslational regulation of CALHM1/3 channel: N-linked glycosylation and S-palmitoylation. Abstract 2021 1
33891658 Zhang M et al. Palmitoylation of the envelope membrane proteins GP5 and M of porcine reproductive and respiratory syndrome virus is essential for virus growth. Abstract 2021 1
33873072 Gök C et al. Insights into the molecular basis of the palmitoylation and depalmitoylation of NCX1. Abstract 2021 1
33707782 Abrami L et al. Palmitoylated acyl protein thioesterase APT2 deforms membranes to extract substrate acyl chains. Abstract 2021 1
33659252 Blaustein M et al. Akt Is S-Palmitoylated: A New Layer of Regulation for Akt. Abstract 2021 1
33423045 Xia Z et al. GNA13 regulates BCL2 expression and the sensitivity of GCB-DLBCL cells to BCL2 inhibitors in a palmitoylation-dependent manner. Abstract 2021 1
33434576 Malgapo MIP et al. Metallo-β-Lactamase Domain-Containing Protein 2 (MBLAC2) is S-palmitoylated and exhibits acyl-CoA hydrolase activity. Abstract 2020 0
33375397 Chai K et al. Palmitoylation of the Bovine Foamy Virus Envelope Glycoprotein Is Required for Viral Replication. Abstract 2020 1
33310888 Nguyen HT et al. Spike glycoprotein and host cell determinants of SARS-CoV-2 entry and cytopathic effects. Abstract 2020 0
33219126 Malgapo MIP et al. Metallo-β-Lactamase Domain-Containing Protein 2 (MBLAC2) is S-palmitoylated and exhibits acyl-CoA hydrolase activity. Abstract 2020 4
33189717 Ayewoh EN et al. S-acylation status of bile acid transporter hASBT regulates its function, metabolic stability, membrane expression, and phosphorylation state. Abstract 2020 1
33185190 Sanders SS et al. The palmitoyl acyltransferase ZDHHC14 controls Kv1-family potassium channel clustering at the axon initial segment. Abstract 2020 2
33207199 Niu J et al. Coupled Control of Distal Axon Integrity and Somal Responses to Axonal Damage by the Palmitoyl Acyltransferase ZDHHC17. Abstract 2020 4
32896381 Kwon H et al. N-myristoylation regulates insulin-induced phosphorylation and ubiquitination of Caveolin-2 for insulin signaling. Abstract 2020 1
32938982 Nelvagal HR et al. Comparative proteomic profiling reveals mechanisms for early spinal cord vulnerability in CLN1 disease. Abstract 2020 0
32944167 Mariscal J et al. Comprehensive palmitoyl-proteomic analysis identifies distinct protein signatures for large and small cancer-derived extracellular vesicles. Abstract 2020 7
32963941 Yuan M et al. ZDHHC12-mediated claudin-3 <i>S</i>-palmitoylation determines ovarian cancer progression. Abstract 2020 2
32976704 Zhou L et al. Selective Enrichment Coupled with Proteomics to Identify S-Acylated Plasma Membrane Proteins in Arabidopsis. Abstract 2020 1
33060596 Li MY et al. Lyn kinase regulates egress of flaviviruses in autophagosome-derived organelles. Abstract 2020 1
33067255 Harada T et al. Palmitoylated CKAP4 regulates mitochondrial functions through an interaction with VDAC2 at ER-mitochondria contact sites. Abstract 2020 1
20580052 McBride CE et al. Palmitoylation of SARS-CoV S protein is necessary for partitioning into detergent-resistant membranes and cell-cell fusion but not interaction with M protein. Abstract 2010 1
33024813 Chen X et al. Protein Palmitoylation Regulates Cell Survival by Modulating XBP1 Activity in Glioblastoma Multiforme. Abstract 2020 1
33029007 Zhang M et al. A STAT3 palmitoylation cycle promotes T<sub>H</sub>17 differentiation and colitis. Abstract 2020 1
33033368 Yeliseev A et al. Thermostability of a recombinant G protein-coupled receptor expressed at high level in mammalian cell culture. Abstract 2020 1
32986127 Sharma C et al. Antioxidant functions of DHHC3 suppress anti-cancer drug activities. Abstract 2020 1
33057424 Webb LG et al. Chikungunya virus antagonizes cGAS-STING mediated type-I interferon responses by degrading cGAS. Abstract 2020 1
33103814 Ho GPH et al. Upregulation of Cellular Palmitoylation Mitigates α-Synuclein Accumulation and Neurotoxicity. Abstract 2020 1
33108395 Wang X et al. p53 promotes ZDHHC1-mediated IFITM3 palmitoylation to inhibit Japanese encephalitis virus replication. Abstract 2020 2
33112630 Santi M et al. Protein Delivery by Peptide-Based Stealth Liposomes: A Biomolecular Insight into Enzyme Replacement Therapy. Abstract 2020 0
1713685 Ruff P et al. Molecular identification of a major palmitoylated erythrocyte membrane protein containing the src homology 3 motif. Abstract 1991 1
24562000 Brigidi GS et al. Palmitoylation of δ-catenin by DHHC5 mediates activity-induced synapse plasticity. Abstract 2014 1
32913120 McClafferty H et al. Site specific deacylation by ABHD17a controls BK channel splice variant activity. Abstract 2020 1
32916275 Suzuki K et al. The promoting role of lysosome-localized c-Src in autophagosome-lysosome fusion. Abstract 2020 1
32838949 Xu Z et al. S-palmitoylation of swine interferon-inducible transmembrane protein is essential for its anti-JEV activity. Abstract 2020 1
32958780 Hao JW et al. CD36 facilitates fatty acid uptake by dynamic palmitoylation-regulated endocytosis. Abstract 2020 1
32958558 Collura KM et al. The palmitoyl acyltransferases ZDHHC5 and ZDHHC8 are uniquely present in DRG axons and control retrograde signaling via the Gp130/JAK/STAT3 pathway. Abstract 2020 2
32845322 Hane M et al. Human-specific Microglial Siglec-11 Transcript Variant has the Potential to affect Polysialic Acid-Mediated Brain Functions at a Distance. Abstract 2020 1
32395856 Wang X et al. A protein palmitoylation cascade regulates microtubule cytoskeleton integrity in Plasmodium. Abstract 2020 1
32248222 Ning W et al. GPS-Palm: a deep learning-based graphic presentation system for the prediction of S-palmitoylation sites in proteins. Abstract 2020 0
32259481 Li Q et al. Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription. Abstract 2020 4
32279353 Sarkar C et al. Cln1-mutations suppress Rab7-RILP interaction and impair autophagy contributing to neuropathology in a mouse model of infantile neuronal ceroid lipofuscinosis. Abstract 2020 3
32283203 Bekhouche B et al. A toxic palmitoylation of Cdc42 enhances NF-κB signaling and drives a severe autoinflammatory syndrome. 2020 0