SwissPalm

Q13308 PTK7_HUMAN

General info Cross-references Sequences Orthologs Ortholog sequences Predictions Palmitoyl-proteomes References

Palmitoyl-proteomes

10/22 articles for human
7 orthologs

Palmitoyl-proteome experiments

Validation experiments

0 experiment
0 ortholog

Curated sites & Enzymes

0 site from validation experiments^*
0 site from palmitoyl-proteomes^*
No PAT known
No APT known
^*In main isoform only

Predictions

Predicted

1 cysteine in main isoform

Predictions

Protein general information from UniProt

Protein names

Inactive tyrosine-protein kinase 7; Colon carcinoma kinase 4, CCK-4; Protein-tyrosine kinase 7; Pseudo tyrosine kinase receptor 7; Tyrosine-protein kinase-like 7

Subcellular location

Membrane (Probable); Cell junction (Probable)

Isoforms & protein length

Isoform 1 (main): 1070 aa; Isoform 2 : 1030 aa; Isoform 3 : 940 aa; Isoform 4 : 1014 aa; Isoform 5 : 816 aa; Isoform 6 : 1078 aa

Known functions

Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis. Interacts with CTNNB1. Colocalizes with MMP14 at cell junctions. Also localizes at the leading edge of migrating cells. Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis. Interacts with CTNNB1. Colocalizes with MMP14 at cell junctions. Also localizes at the leading edge of migrating cells. Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis. Interacts with CTNNB1. Colocalizes with MMP14 at cell junctions. Also localizes at the leading edge of migrating cells.

Cross-references

Source	Identifiers
UniProt gene names	PTK7, CCK4
UniProt secondary AC	A8K974, B7Z477, E9PFZ5, Q13417, Q5T650, Q6IQ54, Q8NFA5, Q8NFA6, Q8NFA7, Q8NFA8
Refseq protein ID	NP_001257327.1, NP_002812.2, NP_690619.1, NP_690620.1, NP_690621.1
IPI ID	IPI00168813, IPI00170814, IPI00174794, IPI00298292, IPI00478565, IPI00946792, IPI00442126, IPI00419941, IPI00384509, IPI00289586, IPI00219694, IPI00168812

Source	Identifiers
Ensembl protein	ENSP00000230418, ENSP00000230419, ENSP00000325992, ENSP00000325462, ENSP00000326029, ENSP00000418754
Ensembl gene	ENSG00000112655

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Isoform sequence alignment

Tip: Hover over an amino acid to display its position!

Orthologs

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UniProt AC	UniProt ID	Orthology source	Organism	Gene names	Protein name	Palmitome articles	Techniques	Predicted
Q8BKG3	PTK7_MOUSE	OrthoDB, OMA, Ensembl, InParanoid, MetaPhors	M. musculus	Ptk7	Inactive tyrosine-protein kinase 7	2/23	3	Yes
Q7JXW8	Q7JXW8_DROME	Ensembl, MetaPhors	D. melanogaster	CT25760, Dmel\CG8964, l(2)SH1639, l(2)SH2 1639, otk2, CG8964, Dmel_CG8964	Off-track2	0/1	0	Yes
Q9SR05	ANX1_ARATH	InParanoid	A. thaliana	ANX1, At3g04690, F7O18.16	Receptor-like protein kinase ANXUR1, EC 2.7.11.1	0/1	0	Yes
Q3E8W4	ANX2_ARATH	InParanoid	A. thaliana	ANX2, At5g28680, F4I4.60	Receptor-like protein kinase ANXUR2, EC 2.7.11.1	0/1	0	Yes
Q9SCZ4	FERON_ARATH	InParanoid	A. thaliana	FER, AAK1, SIR, SRN, At3g51550, F26O13.190	Receptor-like protein kinase FERONIA, EC 2.7.11.1	1/1	1	Yes
Q9FID8	Y5900_ARATH	InParanoid	A. thaliana	At5g39000, MXF12.2	Putative receptor-like protein kinase At5g39000, EC 2.7.11.-	0/1	0	Yes
Q9LK35	THE1_ARATH	InParanoid	A. thaliana	THE1, At5g54380, GA469.3	Receptor-like protein kinase THESEUS 1, EC 2.7.11.-	1/1	1	Yes
Q9LX66	HERK_ARATH	InParanoid	A. thaliana	HERK1, At3g46290, F12M12.260, F18L15.10	Receptor-like protein kinase HERK 1, EC 2.7.11.-	0/1	0	Yes
Q9FID9	Y5389_ARATH	InParanoid	A. thaliana	At5g38990, K15E6.170	Probable receptor-like protein kinase At5g38990, EC 2.7.11.-	0/1	0	Yes
Q9SA72	Y1357_ARATH	InParanoid	A. thaliana	At1g30570, T5I8.2	Probable receptor-like protein kinase At1g30570, EC 2.7.11.-	1/1	1	Yes
Q9FLJ8	Y5613_ARATH	InParanoid	A. thaliana	At5g61350, MFB13.1	Probable receptor-like protein kinase At5g61350, EC 2.7.11.-	0/1	0	No
Q9SJT0	Y2214_ARATH	InParanoid	A. thaliana	At2g21480, F3K23.24	Probable receptor-like protein kinase At2g21480, EC 2.7.11.-	0/1	0	Yes
Q9T020	Y4391_ARATH	InParanoid	A. thaliana	At4g39110, F19H22.210, T22F8.10	Probable receptor-like protein kinase At4g39110, EC 2.7.11.-	0/1	0	No
Q9FLW0	Y5241_ARATH	InParanoid, MetaPhors	A. thaliana	At5g24010, MZF18.11	Probable receptor-like protein kinase At5g24010, EC 2.7.11.-	0/1	0	Yes
O80623	Y2393_ARATH	InParanoid	A. thaliana	At2g39360, F12L6.2	Probable receptor-like protein kinase At2g39360, EC 2.7.11.-	0/1	0	Yes
O22187	Y2232_ARATH	InParanoid	A. thaliana	At2g23200, T20D16.17	Probable receptor-like protein kinase At2g23200, EC 2.7.11.-	0/1	0	Yes
Q9FID5	Y5393_ARATH	InParanoid	A. thaliana	At5g39030, MXF12.40	Probable receptor-like protein kinase At5g39030, EC 2.7.11.-	0/1	0	Yes
Q9FID6	Y5392_ARATH	InParanoid	A. thaliana	At5g39020, MXF12.30	Probable receptor-like protein kinase At5g39020, EC 2.7.11.-	0/1	0	No
P22987	KIN1_SCHPO	MetaPhors	S. pombe	kin1, SPBC4F6.06	Protein kinase kin1	0/1	0	No
Q09024	IMPL2_DROME	MetaPhors	D. melanogaster	ImpL2, CG15009	Neural/ectodermal development factor IMP-L2	0/1	0	No
Q7JQ32	GC76C_DROME	MetaPhors	D. melanogaster	Gyc76C, CG42636	Receptor-type guanylate cyclase Gyc76C, EC 4.6.1.2	0/1	0	Yes
P43298	TMK1_ARATH	MetaPhors	A. thaliana	BLK1, TMK1, At1g66150, F15E12.4	Receptor protein kinase TMK1, EC 2.7.11.1	0/1	0	Yes
Q6R2J8	SRF8_ARATH	MetaPhors	A. thaliana	SRF8, At4g22130, F1N20.230	Protein STRUBBELIG-RECEPTOR FAMILY 8	0/1	0	Yes
Q9C9N5	Y1668_ARATH	MetaPhors	A. thaliana	At1g66830, F4N21.23	Probable inactive leucine-rich repeat receptor-like protein kinase At1g66830	0/1	0	Yes
Q9CAL8	PEK13_ARATH	MetaPhors	A. thaliana	PERK13, RHS10, At1g70460, F24J13.3	Proline-rich receptor-like protein kinase PERK13, EC 2.7.11.1	0/1	0	No
Q9FRI1	Q9FRI1_ARATH	MetaPhors	A. thaliana	F4F7_29, F4F7.29, LRR-RLK, At1g25320	At1g25320/F4F7_17	1/1	1	Yes
Q9SUQ3	Y4374_ARATH	MetaPhors	A. thaliana	At4g23740, F9D16.210	Probable inactive receptor kinase At4g23740	0/1	0	Yes
Q9C8I6	IOS1_ARATH	MetaPhors	A. thaliana	IOS1, At1g51800, F19C24.3	LRR receptor-like serine/threonine-protein kinase IOS1, EC 2.7.11.-	0/1	0	Yes
Q9FGL5	CEPR1_ARATH	MetaPhors	A. thaliana	CEPR1, XIP1, At5g49660, MNI5.4	Receptor protein-tyrosine kinase CEPR1, EC 2.7.10.1	0/1	0	Yes
Q9FF31	LRL21_ARATH	MetaPhors	A. thaliana	LRK10L-2.1, At5g38260, MXA21.5	LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEPTOR-LIKE PROTEIN KINASE-like 2.1, EC 2.7.11.1	0/1	0	No
Q9FFW5	PERK8_ARATH	MetaPhors	A. thaliana	PERK8, At5g38560, MBB18.10	Proline-rich receptor-like protein kinase PERK8, EC 2.7.11.1	0/1	0	No
C0LGG4	Y1518_ARATH	MetaPhors	A. thaliana	At1g51860, T14L22.7	Probable LRR receptor-like serine/threonine-protein kinase At1g51860, EC 2.7.11.1	0/1	0	No
B9DFG5	PTI13_ARATH	MetaPhors	A. thaliana	PTI13, At3g59350, F25L23.210	PTI1-like tyrosine-protein kinase 3, PTI1-3, EC 2.7.10.2	1/1	1	Yes
C0LGJ1	Y1743_ARATH	MetaPhors	A. thaliana	At1g74360, F1M20.4	Probable LRR receptor-like serine/threonine-protein kinase At1g74360, EC 2.7.11.1	0/1	0	No
C0LGM1	C0LGM1_ARATH	MetaPhors	A. thaliana	T2N18.19, T2N18_19, LRR-RLK, At2g37050	Leucine-rich repeat protein kinase family protein	1/1	1	Yes
F4IB71	F4IB71_ARATH	MetaPhors	A. thaliana	At1g51870, T14L22.8, T14L22_8	Protein kinase family protein	0/1	0	Yes
Q9LYN8	EMS1_ARATH	MetaPhors	A. thaliana	EXS, EMS1, ESP, At5g07280, T28J14.220	Leucine-rich repeat receptor protein kinase EMS1, EC 2.7.11.1	0/1	0	No
Q66GN2	LRK64_ARATH	MetaPhors	A. thaliana	LECRK64, LECRKA4.3, At5g01560, F7A7.80	Lectin-domain containing receptor kinase VI.4, LecRK-VI.4, EC 2.7.11.1	0/1	0	Yes
Q9M2S4	LRKS4_ARATH	MetaPhors	A. thaliana	LECRKS4, At3g55550, T22E16.210	L-type lectin-domain containing receptor kinase S.4, LecRK-S.4, EC 2.7.11.1	0/1	0	No
Q9SX57	Q9SX57_ARATH	MetaPhors	A. thaliana	At1g48220, F11A17.22, F11A17_22	F11A17.22 protein	0/1	0	Yes
Q9SY95	Y1155_ARATH	MetaPhors	A. thaliana	At1g61550, T25B24.10	G-type lectin S-receptor-like serine/threonine-protein kinase At1g61550, EC 2.7.11.1	0/1	0	Yes
O81905	SD18_ARATH	MetaPhors	A. thaliana	SD18, ARK3, At4g21380, T6K22.110	Receptor-like serine/threonine-protein kinase SD1-8, EC 2.7.11.1	0/1	0	Yes
Q9C823	Y1523_ARATH	MetaPhors	A. thaliana	At1g52310, F19K6.8	C-type lectin receptor-like tyrosine-protein kinase At1g52310, EC 2.7.10.1	0/1	0	Yes
Q9FM43	Q9FM43_ARATH	MetaPhors	A. thaliana	MNF13.60, MNF13_60, At5g40540	Protein kinase ATN1	0/1	0	Yes
Q3E9X6	CRK21_ARATH	MetaPhors	A. thaliana	CRK21, At4g23290, F21P8.180	Cysteine-rich receptor-like protein kinase 21, Cysteine-rich RLK21, EC 2.7.11.-	0/1	0	Yes
Q7X8C5	WAKLB_ARATH	MetaPhors	A. thaliana	WAKL2, At1g16130, T24D18.21	Wall-associated receptor kinase-like 2, EC 2.7.11.-	0/1	0	Yes
Q9C5S8	CRK5_ARATH	MetaPhors	A. thaliana	CRK5, RLK6, At4g23130, F21P8.20, F7H19.320	Cysteine-rich receptor-like protein kinase 5, Cysteine-rich RLK5, EC 2.7.11.-	0/1	0	No
Q8RY17	WAKLI_ARATH	MetaPhors	A. thaliana	WAKL22, RFO1, At1g79670, F20B17_27	Wall-associated receptor kinase-like 22, EC 2.7.11.-	0/1	0	Yes
Q8S9L6	CRK29_ARATH	MetaPhors	A. thaliana	CRK29, At4g21410, F18E5.30, T6K22.140	Cysteine-rich receptor-like protein kinase 29, Cysteine-rich RLK29, EC 2.7.11.-	0/1	0	Yes
Q9C9L5	WAKLH_ARATH	MetaPhors	A. thaliana	WAKL9, At1g69730, T6C23.7	Wall-associated receptor kinase-like 9, EC 2.7.11.-	0/1	0	Yes
Q9LRP3	Y3174_ARATH	MetaPhors	A. thaliana	At3g17420, MTO12.1	Probable receptor-like protein kinase At3g17420, EC 2.7.11.1	0/1	0	No
Q9S9M1	WAKLE_ARATH	MetaPhors	A. thaliana	WAKL5, At1g16160, T24D18.24	Wall-associated receptor kinase-like 5, EC 2.7.11.-	0/1	0	Yes
Q9SA26	Q9SA26_ARATH	MetaPhors	A. thaliana	At1g16270, F3O9.7, F3O9_7	F3O9.7 protein	0/1	0	No
Q9SIB6	PBL6_ARATH	MetaPhors	A. thaliana	PBL6, AK14, At2g28590	Probable serine/threonine-protein kinase PBL6, EC 2.7.11.1	0/1	0	Yes
Q8VYA3	WAKLJ_ARATH	MetaPhors	A. thaliana	WAKL10, At1g79680, F20B17.10	Wall-associated receptor kinase-like 10, EC 2.7.11.-	0/1	0	Yes
Q9LN59	WAKLK_ARATH	MetaPhors	A. thaliana	WAKL11, At1g19390, F18O14.11	Putative wall-associated receptor kinase-like 11, EC 2.7.11.-	0/1	0	Yes
Q0WNY5	WAKLN_ARATH	MetaPhors	A. thaliana	WAKL18, At4g31110, F6E21.30	Wall-associated receptor kinase-like 18, EC 2.7.11.-	0/1	0	Yes
C0LGG7	Y1534_ARATH	MetaPhors	A. thaliana	At1g53420, F12M16.30	Probable LRR receptor-like serine/threonine-protein kinase At1g53420, EC 2.7.11.1	0/1	0	Yes
Q9ZP16	CRK11_ARATH	MetaPhors	A. thaliana	CRK11, RLK3, At4g23190, F21P8.80	Cysteine-rich receptor-like protein kinase 11, Cysteine-rich RLK11, EC 2.7.11.-	0/1	0	Yes
O49564	CRK27_ARATH	MetaPhors	A. thaliana	CRK27, At4g21230, F7J7.170	Cysteine-rich receptor-like protein kinase 27, Cysteine-rich RLK27, EC 2.7.11.-	0/1	0	Yes
Q6NKZ9	Y4345_ARATH	MetaPhors	A. thaliana	At4g34500, T4L20.80	Probable receptor-like serine/threonine-protein kinase At4g34500, EC 2.7.11.1	0/1	0	Yes
C0LGV0	Y5487_ARATH	MetaPhors	A. thaliana	At5g48740, K24G6.7	Probable LRR receptor-like serine/threonine-protein kinase At5g48740, EC 2.7.11.1	0/1	0	Yes
O23081	CRK41_ARATH	MetaPhors	A. thaliana	CRK41, At4g00970, A_TM018A10.18, T18A10.9	Cysteine-rich receptor-like protein kinase 41, Cysteine-rich RLK41, EC 2.7.11.-	0/1	0	Yes
C0LGD7	Y1684_ARATH	MetaPhors	A. thaliana	At1g06840, F4H5.8	Probable LRR receptor-like serine/threonine-protein kinase At1g06840, EC 2.7.11.1	0/1	0	Yes
Q8GXQ3	WAKLF_ARATH	MetaPhors	A. thaliana	WAKL6, At1g16110, T24D18.19, T24D18_30	Wall-associated receptor kinase-like 6, EC 2.7.11.-	0/1	0	Yes
Q9LPZ3	Y1141_ARATH	MetaPhors	A. thaliana	At1g11410, T23J18.8	G-type lectin S-receptor-like serine/threonine-protein kinase At1g11410, EC 2.7.11.1	0/1	0	Yes
F4I3K4	F4I3K4_ARATH	MetaPhors	A. thaliana	At1g56145	Leucine-rich repeat transmembrane protein kinase	0/1	0	Yes
A0A178UAF6	A0A178UAF6_ARATH	MetaPhors	A. thaliana	AXX17_At5g67350, AN1_LOCUS27066, AT9943_LOCUS23311, C24_LOCUS26894		0/1	0	No
A0A178UE09	A0A178UE09_ARATH	MetaPhors	A. thaliana	AXX17_At5g56880, AN1_LOCUS26049, C24_LOCUS25875	Protein kinase domain-containing protein	0/1	0	No
D3ZHG3	D3ZHG3_RAT	OrthoDB, Ensembl	R. norvegicus	Srf_predicted, rCG_43517, Ptk7	Protein tyrosine kinase 7	0/3	0	Yes
E2RMT2	E2RMT2_CANLF	OrthoDB, Ensembl	C. familiaris	PTK7	Uncharacterized protein	0/1	0	Yes
F1MWK8	F1MWK8_BOVIN	OrthoDB, OMA, Ensembl, InParanoid, MetaPhors	B. taurus	PTK7	Protein tyrosine kinase 7	0/2	0	Yes
Q6AWJ9	PTK7_DROME	OrthoDB, OMA, Ensembl, InParanoid, MetaPhors	D. melanogaster	otk, CG8967	Tyrosine-protein kinase-like otk	0/1	0	Yes
F1PHH3	F1PHH3_CANLF	OMA, Ensembl, InParanoid	C. familiaris	PTK7	Uncharacterized protein	0/1	0	Yes

Ortholog sequence alignment (CLUSTALW)

Cysteine summary and predictions

Pos in alignment	64	112	161	211	212	221	257	312	354	402	444	492	524	535
Subcell. location	E	E	E	E	E	E	E	E	E	E	E	E	E	E
Disulfide	yes	yes	yes	yes	no	no	yes	yes	yes	yes	yes	yes	no	yes
PSIPRED v.4.02 prediction													coil
UniProt secondary structure													NA
Pos in isoform 1 [Main] CSS-Palm 4.0 PalmPred	Cys⁵³	Cys¹⁰¹	Cys¹⁵⁰	Cys²⁰⁰ HC	Cys²⁰¹ HC	Cys²¹⁰	Cys²⁴⁶ HC	Cys³⁰¹	Cys³⁴³	Cys³⁹¹	Cys⁴³³	Cys⁴⁸¹	Cys⁵¹³	Cys⁵²⁴
Pos in isoform 2 CSS-Palm 4.0 PalmPred	Cys⁵³	Cys¹⁰¹	Cys¹⁵⁰	Cys²⁰⁰ HC	Cys²⁰¹ HC	Cys²¹⁰	Cys²⁴⁶ HC	Cys³⁰¹	Cys³⁴³	Cys³⁹¹	Cys⁴³³	Cys⁴⁸¹
Pos in isoform 3 CSS-Palm 4.0 PalmPred	Cys⁵³	Cys¹⁰¹	Cys¹⁵⁰	Cys²⁰⁰ HC	Cys²⁰¹ HC	Cys²¹⁰	Cys²⁴⁶ HC	Cys³⁰¹	Cys³⁴³	Cys³⁹¹
Pos in isoform 4 CSS-Palm 4.0 PalmPred	Cys⁵³	Cys¹⁰¹	Cys¹⁵⁰	Cys²⁰⁰ HC	Cys²⁰¹ HC	Cys²¹⁰	Cys²⁴⁶ HC	Cys³⁰¹	Cys³⁴³	Cys³⁹¹	Cys⁴³³	Cys⁴⁸¹	Cys⁵¹³	Cys⁵²⁴
Pos in isoform 5 CSS-Palm 4.0 PalmPred	Cys⁵³	Cys¹⁰¹	Cys¹⁵⁰	Cys²⁰⁰ HC	Cys²⁰¹ HC	Cys²¹⁰	Cys²⁴⁶ HC	Cys³⁰¹	Cys³⁴³	Cys³⁹¹	Cys⁴³³	Cys⁴⁸¹	Cys⁵¹³	Cys⁵²⁴
Pos in isoform 6 CSS-Palm 4.0 PalmPred	Cys⁶¹	Cys¹⁰⁹	Cys¹⁵⁸	Cys²⁰⁸ HC	Cys²⁰⁹ HC	Cys²¹⁸	Cys²⁵⁴ HC	Cys³⁰⁹	Cys³⁵¹	Cys³⁹⁹	Cys⁴⁴¹	Cys⁴⁸⁹	Cys⁵²¹	Cys⁵³²

Pos in alignment	581	624	675	681	737	741	759	876	922	947	1043	1054
Subcell. location	E	E	E	E	C	C	C	C	C	C	C	C
Disulfide	yes	yes	yes	no	no	no	no	no	no	no	no	no
PSIPRED v.4.02 prediction											helix
UniProt secondary structure											NA
Pos in isoform 1 [Main] CSS-Palm 4.0 PalmPred	Cys⁵⁷⁰	Cys⁶¹³	Cys⁶⁶⁴	Cys⁶⁷⁰	Cys⁷²⁶ HC	Cys⁷³⁰ MC	Cys⁷⁴⁸	Cys⁸⁶⁵	Cys⁹¹¹	Cys⁹³⁶	Cys¹⁰³²	Cys¹⁰⁴³
Pos in isoform 2 CSS-Palm 4.0 PalmPred	Cys⁵³⁰	Cys⁵⁷³	Cys⁶²⁴	Cys⁶³⁰	Cys⁶⁸⁶ HC	Cys⁶⁹⁰ MC	Cys⁷⁰⁸	Cys⁸²⁵	Cys⁸⁷¹	Cys⁸⁹⁶	Cys⁹⁹²	Cys¹⁰⁰³
Pos in isoform 3 CSS-Palm 4.0 PalmPred	Cys⁴⁴⁰	Cys⁴⁸³	Cys⁵³⁴	Cys⁵⁴⁰	Cys⁵⁹⁶ HC	Cys⁶⁰⁰ MC	Cys⁶¹⁸	Cys⁷³⁵	Cys⁷⁸¹	Cys⁸⁰⁶	Cys⁹⁰²	Cys⁹¹³
Pos in isoform 4 CSS-Palm 4.0 PalmPred	Cys⁵⁷⁰	Cys⁶¹³			Cys⁶⁷⁰ HC	Cys⁶⁷⁴ MC	Cys⁶⁹²	Cys⁸⁰⁹	Cys⁸⁵⁵	Cys⁸⁸⁰	Cys⁹⁷⁶	Cys⁹⁸⁷
Pos in isoform 5 CSS-Palm 4.0 PalmPred	Cys⁵⁷⁰	Cys⁶¹³	Cys⁶⁶⁴	Cys⁶⁷⁰	Cys⁷²⁶	Cys⁷³⁰	Cys⁷⁴⁸
Pos in isoform 6 CSS-Palm 4.0 PalmPred	Cys⁵⁷⁸	Cys⁶²¹	Cys⁶⁷²	Cys⁶⁷⁸	Cys⁷³⁴ HC	Cys⁷³⁸ MC	Cys⁷⁵⁶	Cys⁸⁷³	Cys⁹¹⁹	Cys⁹⁴⁴	Cys¹⁰⁴⁰	Cys¹⁰⁵¹

Legend

Subcell. location

U Undefined E Extracellular/Lumenal T Transmembrane C Cytosolic/Nuclear

Prediction confidence

Cysteine position: Predicted (high confidence prediction with CSS-Palm or/and PalmPred) and validated (in terms of disulfide bonds and cellular location) / Predicted but not validated (in terms of disulfide bond and cellular location) / Not predicted
CSS-Palm 4.0: High confidence, Medium confidence, Low confidence, Not predicted.
PalmPred: High confidence (score > 0.4), Medium confidence (0.1 < score < 0.4), Low confidence (score < 0.1), Not predicted.

Palmitoyl-proteome experiments

List of palmitoyl-proteomes

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ID of the experiment	Reference	Year	Organism	Cell type	Subcellular location	Technique(s)	Found?	In list	All lists
SPalmE:14	Roth AF et al.	2006	Saccharomyces cerevisiae	Isogenic LRB759	Total membrane	ABE	x		HC HC: 48 hits
SPalmE:13	Kang R et al.	2008	Rattus norvegicus	Cortical neuron	Synaptosomal membrane	ABE	x		HC: 107 hits LC: 308 hits
SPalmE:6	Martin BR et al.	2009	Homo sapiens	Jurkat	Total membrane	Click chemistry	Found	in LC	HC: 127 hits LC: 188 hits List: 0 hits
SPalmE:1	Yang W et al.	2010	Homo sapiens	DU145	Total membrane	ABE	x		HC: 162 hits LC: 218 hits
SPalmE:10	Yount JS et al.	2010	Mus musculus	Dendritic cell	Total cell lysate	Click chemistry	x		HC: 59 hits LC: 105 hits
SPalmE:578	Yang W et al.	2010	Homo sapiens	DU145	Lipid raft	ABE	x		HC: 102 hits LC: 73 hits
SPalmE:577	Yang W et al.	2010	Homo sapiens	DU145	Non-lipid raft	ABE	Found	in HC	HC: 63 hits LC: 147 hits
SPalmE:12	Martin BR et al.	2011	Mus musculus	BW5147-derived mouse T-cell hybridoma cell	Total membrane	Click chemistry	x		HC HC: 352 hits LC LC: 8 hits
SPalmE:2	Dowal L et al.	2011	Homo sapiens	Platelet	Total membrane	ABE	x		List: 214 hits
SPalmE:8	Merrick BA et al.	2011	Mus musculus	Macrophage Raw 264.7	Total membrane	ABE	x		List: 69 hits
SPalmE:511	Emmer BT et al.	2011	Trypanosoma brucei brucei	NA	Total cell lysate	ABE	x		List: 126 hits
SPalmE:5	Forrester MT et al.	2011	Homo sapiens	HEK293	Total membrane	ARAC	x		List: 69 hits
SPalmE:7	Wilson JP et al.	2011	Homo sapiens	Jurkat	Total cell lysate	Click chemistry	x		HC: 164 hits LC: 178 hits
SPalmE:3	Ivaldi C et al.	2012	Homo sapiens	B-cell	Total membrane	ABE	x		HC HC: 93 hits
SPalmE:580	Jones ML et al.	2012	Plasmodium falciparum	Whole organism	Total cell lysate	Click chemistry, SILAC	x		HC: 79 hits LC: 89 hits
SPalmE:162	Jones ML et al.	2012	Plasmodium falciparum	Whole organism	Total cell lysate	ABE	x		HC: 100 hits LC: 217 hits
SPalmE:11	Li Y et al.	2012	Mus musculus	Neural stem cell	Total cell lysate	Click chemistry	x		HC HC: 254 hits
SPalmE:4	Marin EP et al.	2012	Homo sapiens	Umbilical vein blood	NA	ABE	x		List: 154 hits
SPalmE:9	Ren W et al.	2013	Mus musculus	3T3-L1 and epididymal fat pads	Total membrane	ARAC	x		List: 664 hits
SPalmE:15	Hemsley PA et al.	2013	Arabidopsis thaliana	Heyn Col-4 ecotype root cell suspension	Microsomal membrane	ABE	Ortholog	in LC,MC [Y1357, C0LGM1, PTI13, Q9FRI1, FERON, THE1]	HC: 122 hits MC: 94 hits LC: 366 hits
SPalmE:119	Wan J et al.	2013	Mus musculus	Brain	Total cell lysate	ABE	x		List: 378 hits
SPalmE:160	Zhang MM et al.	2013	Schizosaccharomyces pombe	Whole organism	Total cell lysate	Click chemistry	x		List: 238 hits
SPalmE:507	Chesarino NM et al.	2014	Mus musculus	DC2.4	Total cell lysate	Click chemistry	x		List: 246 hits
SPalmE:508	Chesarino NM et al.	2014	Mus musculus	MEF	Total cell lysate	Click chemistry	Ortholog	in List [PTK7]	List: 436 hits
SPalmE:184	Wei X et al.	2014	Homo sapiens	HUVEC	Total cell lysate	ABE	x		Palm decreased: 40 hits Palm increased: 33 hits List: 367 hits
SPalmE:619	Peng T et al.	2015	Homo sapiens	HEK293	Total cell lysate	Alk16 Labeling	Found	in List	List: 354 hits
SPalmE:504	Serwa RA et al.	2015	Homo sapiens	RPE-1	Total cell lysate	SILAC, 16-HDYA labeling	Found	in List	List: 1348 hits
SPalmE:620	Peng T et al.	2015	Homo sapiens	HEK293	Total cell lysate	Photo cleavable x-alk16 labeling	Found	in List	List: 354 hits
SPalmE:506	Morrison E et al.	2015	Homo sapiens	Jurkat	Total cell lysate	Click chemistry, SILAC	Found	in List	List: 226 hits
SPalmE:540	Gould NS et al.	2015	Mus musculus	Liver	Total cell lysate	APE	x		List: 780 hits
SPalmE:529	Colquhoun DR et al.	2015	Homo sapiens	174 x CEM.T1	Total cell lysate	Click-IT Palmitic Acid labeling	x		List: 113 hits
SPalmE:510	Santiago-Tirado FH et al.	2015	Cryptococcus neoformans	NA	Total cell lysate	Click chemistry	x		List: 354 hits
SPalmE:509	Santiago-Tirado FH et al.	2015	Cryptococcus neoformans	NA	Total cell lysate	Click chemistry	x		List: 426 hits
SPalmE:505	Morrison E et al.	2015	Homo sapiens	Primary CD4 + T cells	Total cell lysate	ABE, In gel SILAC labeling	x		List: 274 hits
SPalmE:536	Foe IT et al.	2015	Toxoplasma gondii	NA	Total membrane	Click chemistry	x		HC: 210 hits MC: 72 hits
SPalmE:902	Caballero MC et al.	2016	Toxoplasma gondii	whole parasite lysates	NA	ABE	x		HC: 164 hits
SPalmE:829	Upadhyay S et al.	2016	Aspergillus fumigatus	Conidia	NA	ABE	x		List: 133 hits
SPalmE:724	Fang C et al.	2016	Homo sapiens	SW480	NA	ARAC	x		List: 100 hits
SPalmE:909	Thinon E et al.	2016	Mus musculus	Macrophage Raw 264.7	Total cell lysate	Alk16 Labeling	x		HC: 197 hits MC: 143 hits LC: 302 hits
SPalmE:723	Hernandez JL et al.	2016	Homo sapiens	MCF7	Total cell lysate	Alk16 Labeling	Found	in List	List: 1353 hits
SPalmE:698	Pinner AL et al.	2016	Homo sapiens	Brain	Total cell lysate	ABE	x		List: 216 hits
SPalmE:993	Shen LF et al.	2017	Mus musculus	Liver	Total membrane	ARAC	x		ZDHHC13 substrates: 16 hits
SPalmE:903	Collins MO et al.	2017	Mus musculus	Forebrain	NA	ABE	x		HC: 1079 hits
SPalmE:907	Edmonds MJ et al.	2017	Rattus norvegicus	Brain	NA	ARAC	x		List: 95 hits
SPalmE:906	Edmonds MJ et al.	2017	Rattus norvegicus	Brain	NA	ABE	x		List: 193 hits
SPalmE:855	Shen LF et al.	2017	Mus musculus	Liver	Total membrane	ARAC	x		List: 865 hits
SPalmE:1183	Thinon E et al.	2018	Homo sapiens	HeLa	Total cell lysate	NH2OH cleavage of thioester bond, Alk16 Labeling	x		HC: 132 hits MC: 138 hits LC: 110 hits
SPalmE:1184	Thinon E et al.	2018	Homo sapiens	HeLa	Total cell lysate	ARAC	x		HC: 545 hits MC: 415 hits LC: 219 hits
SPalmE:1182	Thinon E et al.	2018	Mus musculus	Macrophage Raw 264.7	Total cell lysate	ARAC	x		HC: 198 hits MC: 143 hits LC: 120 hits
SPalmE:1186	Thinon E et al.	2018	Mus musculus	Macrophage Raw 264.7	Total cell lysate	NH2OH cleavage of thioester bond, Alk16 Labeling	x		HC: 177 hits MC: 162 hits LC: 123 hits
SPalmE:1181	Thinon E et al.	2018	Mus musculus	Macrophage Raw 264.7	Total cell lysate	NH2OH cleavage of thioester bond, Alk16 Labeling	x		HC: 244 hits MC: 187 hits LC: 120 hits
SPalmE:1191	Won SJ et al.	2018	Homo sapiens	HEK293T	Total cell lysate	Click chemistry	x		List: 195 hits
SPalmE:1192	Won SJ et al.	2018	Homo sapiens	HAP1	Total cell lysate	Click chemistry	x		List: 984 hits
SPalmE:1193	Won SJ et al.	2018	Homo sapiens	HAP1	Total cell lysate	ARAC	x		List: 1394 hits
SPalmE:1194	Won SJ et al.	2018	Homo sapiens	HAP1	Total cell lysate	ARAC,	x		List: 1404 hits
SPalmE:1203	Zhang X et al.	2018	Mus musculus	Brain	Total membrane	Enrichment by magnetic nanoparticles	x		HC: 917 hits MC: 352 hits LC: 15 hits
SPalmE:1259	Dumoulin A et al.	2018	Mus musculus	F11	Total membrane	ABE, NH2OH cleavage of thioester bond, LC-MS	x		HC: 1 hits MC: 10 hits LC: 4 hits
SPalmE:1260	Wang Z et al.	2018	Bos taurus	Lens fiber cell	Total cell lysate	ABE, NH2OH cleavage of thioester bond, LC-MS	x		List: 52 hits
SPalmE:920	Sobocińska J et al.	2018	Mus musculus	Macrophage Raw 264.7	Total cell lysate	Click chemistry	x		LPS treatment: 646 hits
SPalmE:919	Sobocińska J et al.	2018	Mus musculus	Macrophage Raw 264.7	Total cell lysate	Click chemistry	x		List: 646 hits
SPalmE:908	Sobocińska J et al.	2018	Mus musculus	Macrophage Raw 264.7	Total cell lysate	Click chemistry	x		Palm. up with LPS: 156 hits Palm. down with LPS: 189 hits
SPalmE:1185	Thinon E et al.	2018	Homo sapiens	HeLa	Total cell lysate	NH2OH cleavage of thioester bond, LC-MS, Alk16 Labeling	x		Chymotrypsin: 286 hits Trypsin: 1291 hits
SPalmE:1187	Thinon E et al.	2018	Mus musculus	Macrophage Raw 264.7	Total cell lysate	ARAC	x		HC: 281 hits MC: 139 hits LC: 113 hits
SPalmE:1303	Zaręba-Kozioł M et al.	2019	Mus musculus	Brain	Postsynaptic density fraction	ABE, NH2OH cleavage of thioester bond, LC-MS	x
SPalmE:1270	Strassburger K et al.	2019	Drosophila melanogaster	Circa 160 L2 larvae	Total cell lysate	ABE, NH2OH cleavage of thioester bond, PAT KO, MS	x		List: 13 hits
SPalmE:1266	Strassburger K et al.	2019	Drosophila melanogaster	Circa 160 L2 larvae	Total cell lysate	ABE, NH2OH cleavage of thioester bond, PAT KO, MS	x		List: 157 hits
SPalmE:1265	Wang J et al.	2019	Mus musculus	3T3-L1	Total membrane	MS, BioID	x		List: 9 hits
SPalmE:1333	Zaręba-Kozioł M et al.	2019	Mus musculus	Brain	Postsynaptic density fraction	ABE, NH2OH cleavage of thioester bond, LC-MS	x
SPalmE:1433	Zhou B et al.	2019	Homo sapiens	LNCaP	Total cell lysate	NH2OH cleavage of thioester bond, LC-MS, LB-ABE, ABE	Found	in List	List: 2929 hits
SPalmE:1432	Zhou B et al.	2019	Homo sapiens	LNCaP	Total cell lysate	ABE, SILAC, NH2OH cleavage of thioester bond, LC-MS	Found	in List	List: 590 hits
SPalmE:1434	Wegleiter T et al.	2019	Mus musculus	Neural stem cell	Total cell lysate	ABE, NH2OH cleavage of thioester bond, LC-MS	x		List: 370 hits
SPalmE:1438	Mariscal J et al.	2020	Homo sapiens	PC3	Total membrane	ARAC, NH2OH cleavage of thioester bond, LC-MS, LB-ABE	Found	in HC	HC: 1837 hits
SPalmE:1439	Mariscal J et al.	2020	Homo sapiens	PC3	Large Extracellular Vesicles	ARAC, NH2OH cleavage of thioester bond, LC-MS, LB-ABE	Found	in HC	HC: 1350 hits
SPalmE:1440	Mariscal J et al.	2020	Homo sapiens	PC3	Small Extracellular Vesicles	ARAC, NH2OH cleavage of thioester bond, LC-MS, LB-ABE	x		HC: 600 hits
SPalmE:1435	Morrison E et al.	2020	Homo sapiens	Jurkat	Total cell lysate	ABE, NH2OH cleavage of thioester bond, LC-MS, SILAC	Found	in Unstimulated	Unstimulated: 37 hits
SPalmE:1436	Morrison E et al.	2020	Homo sapiens	Jurkat	Total cell lysate	ABE, NH2OH cleavage of thioester bond, LC-MS, SILAC	Found	in List	List: 185 hits
SPalmE:1458	Morrison E et al.	2020	Homo sapiens	Jurkat	Total cell lysate	ABE, NH2OH cleavage of thioester bond, LC-MS, SILAC	x		Stimulated: 148 hits
SPalmE:1437	Mariscal J et al.	2020	Homo sapiens	PC3	Total cell lysate	ARAC, NH2OH cleavage of thioester bond, LC-MS, LB-ABE	Found	in HC	HC: 1869 hits
SPalmE:1450	Zaręba-Kozioł M et al.	2021	Mus musculus	Brain	Synaptoneurosomal fraction	ABE, NH2OH cleavage of thioester bond, LC-MS	x		List: 1093 hits
SPalmE:1444	Miles MR et al.	2021	Homo sapiens	Heart	Total cell lysate	ARAC, NH2OH cleavage of thioester bond, LC-MS	x		List: 687 hits
SPalmE:1447	Pradhan AJ et al.	2021	Homo sapiens	HT-29	Total cell lysate	Labeling of substrate with C20 AlkFA (Alk-18), LC-MS	Found	in List	List: 1173 hits
SPalmE:1448	Pradhan AJ et al.	2021	Homo sapiens	HT-29	Total cell lysate	Labeling of substrate with C20 AlkFA (Alk-18), LC-MS	Found	in List	List: 770 hits
SPalmE:1449	Ripamonti M et al.	2021	Mus musculus	NIH-3T3	Total cell lysate	ARAC, NH2OH cleavage of thioester bond, LC-MS	x		List: 199 hits
SPalmE:1445	Miles MR et al.	2021	Rattus norvegicus	Heart	Total cell lysate	ARAC, NH2OH cleavage of thioester bond, LC-MS	x		List: 399 hits
SPalmE:1451	Zaręba-Kozioł M et al.	2021	Mus musculus	Brain	Synaptoneurosomal fraction	ABE, NH2OH cleavage of thioester bond, LC-MS	x		List: 1048 hits
SPalmE:1452	Zaręba-Kozioł M et al.	2021	Mus musculus	Brain	Synaptoneurosomal fraction	ABE, NH2OH cleavage of thioester bond, LC-MS	x		List: 1112 hits
SPalmE:1453	Zaręba-Kozioł M et al.	2021	Mus musculus	Brain	Synaptoneurosomal fraction	ABE, NH2OH cleavage of thioester bond, LC-MS	x		List: 1040 hits
SPalmE:1455	Ziemlińska E et al.	2021	Mus musculus	Liver	Total membrane	ABE, NH2OH cleavage of thioester bond, LC-MS	x		HC: 850 hits MC: 303 hits LC: 21 hits
SPalmE:1446	Miles MR et al.	2021	Canis familiaris	Heart	Total cell lysate	ARAC, NH2OH cleavage of thioester bond, LC-MS	x		List: 464 hits
SPalmE:1454	Ziemlińska E et al.	2021	Mus musculus	Liver	Total membrane	ABE, NH2OH cleavage of thioester bond, LC-MS	x		HC: 675 hits MC: 360 hits LC: 27 hits
SPalmE:1443	Uzbekova S et al.	2021	Bos taurus	Bovine follicular cells	Total cell lysate	ABE, NH2OH cleavage of thioester bond, LC-MS	x		List: 80 hits
SPalmE:1456	Gao J et al.	2022	Mus musculus	Testis	Total cell lysate	ABE, NH2OH cleavage of thioester bond, LC-MS	x		HC: 4107 hits
SPalmE:1442	Gorenberg EL et al.	2022	Mus musculus	Brain	Total cell lysate	ARAC, NH2OH cleavage of thioester bond, LC-MS	x		List: 1597 hits
SPalmE:1441	Gorenberg EL et al.	2022	Mus musculus	Brain	Synaptic fraction	ARAC, NH2OH cleavage of thioester bond, LC-MS	x		List: 1378 hits
SPalmE:1457	Gao J et al.	2022	Mus musculus	Testis	Total cell lysate	ABE, NH2OH cleavage of thioester bond, LC-MS	Ortholog	in HC [PTK7]	HC: 3870 hits

Summary table by organism

Organism	Total number of palmitoyl-proteome articles	Total number of palmitoyl-proteomes	Number of palmitoyl-proteomes containing this protein or an ortholog	% of palmitoyl-proteomes containing this protein or an ortholog	Orthologs
S. cerevisiae S288c	1	1	0	0.0	NA
R. norvegicus	3	4	0	0.0	NA
H. sapiens	22	38	16	42.1	NA
M. musculus	23	37	2	5.4	PTK7_MOUSE
T. brucei brucei	1	1	0	0.0	NA
P. falciparum	1	2	0	0.0	NA
A. thaliana	1	1	1	100.0	Y1357_ARATH , C0LGM1_ARATH , PTI13_ARATH , Q9FRI1_ARATH , FERON_ARATH , THE1_ARATH
S. pombe	1	1	0	0.0	NA
C. neoformans var. grubii serotype A strain H99	1	2	0	0.0	NA
T. gondii	2	2	0	0.0	NA
A. fumigatus	1	1	0	0.0	NA
B. taurus	2	2	0	0.0	NA
D. melanogaster	1	2	0	0.0	NA
C. familiaris	1	1	0	0.0	NA

References

Authors	Year	Reference title	PMID
Kang R et al.	2008	Neural palmitoyl-proteomics reveals dynamic synaptic palmitoylation.	19092927
Ren W et al.	2013	Proteomic analysis of protein palmitoylation in adipocytes.	23599907
Marin EP et al.	2012	Endothelial cell palmitoylproteomic identifies novel lipid-modified targets and potential substrates for protein acyl transferases.	22496122
Li Y et al.	2012	DHHC5 protein palmitoylates flotillin-2 and is rapidly degraded on induction of neuronal differentiation in cultured cells.	22081607
Martin BR et al.	2011	Global profiling of dynamic protein palmitoylation.	22056678
Dowal L et al.	2011	Proteomic analysis of palmitoylated platelet proteins.	21813449
Merrick BA et al.	2011	Proteomic profiling of S-acylated macrophage proteins identifies a role for palmitoylation in mitochondrial targeting of phospholipid scramblase 3.	21785166
Wilson JP et al.	2011	Proteomic analysis of fatty-acylated proteins in mammalian cells with chemical reporters reveals S-acylation of histone H3 variants.	21076176
Forrester MT et al.	2011	Site-specific analysis of protein S-acylation by resin-assisted capture.	21044946
Yount JS et al.	2010	Palmitoylome profiling reveals S-palmitoylation-dependent antiviral activity of IFITM3.	20601941
Yang W et al.	2010	Proteome scale characterization of human S-acylated proteins in lipid raft-enriched and non-raft membranes.	19801377
Martin BR et al.	2009	Large-scale profiling of protein palmitoylation in mammalian cells.	19137006
Roth AF et al.	2006	Global analysis of protein palmitoylation in yeast.	16751107
Hemsley PA et al.	2013	A proteomic approach identifies many novel palmitoylated proteins in Arabidopsis.	23252521
Ivaldi C et al.	2012	Proteomic analysis of S-acylated proteins in human B cells reveals palmitoylation of the immune regulators CD20 and CD23.	22615937
Wan J et al.	2013	Tracking brain palmitoylation change: predominance of glial change in a mouse model of Huntington's disease.	24211138
Zhang MM et al.	2013	Quantitative control of protein S-palmitoylation regulates meiotic entry in fission yeast.	23843742
Jones ML et al.	2012	Analysis of protein palmitoylation reveals a pervasive role in Plasmodium development and pathogenesis.	22901544
Wei X et al.	2014	Insulin-regulated protein palmitoylation impacts endothelial cell function.	24357059
Serwa RA et al.	2015	Systems Analysis of Protein Fatty Acylation in Herpes Simplex Virus-Infected Cells Using Chemical Proteomics.	26256475
Morrison E et al.	2015	Quantitative analysis of the human T cell palmitome.	26111759
Chesarino NM et al.	2014	Chemoproteomics reveals Toll-like receptor fatty acylation.	25371237
Santiago-Tirado FH et al.	2015	A Single Protein S-acyl Transferase Acts through Diverse Substrates to Determine Cryptococcal Morphology, Stress Tolerance, and Pathogenic Outcome.	25970403
Emmer BT et al.	2011	Global analysis of protein palmitoylation in African trypanosomes.	21193548
Colquhoun DR et al.	2015	Bioorthogonal mimetics of palmitoyl-CoA and myristoyl-CoA and their subsequent isolation by click chemistry and characterization by mass spectrometry reveal novel acylated host-proteins modified by HIV-1 infection.	25914232
Foe IT et al.	2015	Global Analysis of Palmitoylated Proteins in Toxoplasma gondii.	26468752
Gould NS et al.	2015	Site-Specific Proteomic Mapping Identifies Selectively Modified Regulatory Cysteine Residues in Functionally Distinct Protein Networks.	26165157
Peng T et al.	2015	Bifunctional fatty acid chemical reporter for analyzing S-palmitoylated membrane protein-protein interactions in mammalian cells.	25575299
Pinner AL et al.	2016	Decreased protein S-palmitoylation in dorsolateral prefrontal cortex in schizophrenia.	26876311
Hernandez JL et al.	2016	Correlated S-palmitoylation profiling of Snail-induced epithelial to mesenchymal transition.	27030425
Fang C et al.	2016	Identification of Palmitoylated Transitional Endoplasmic Reticulum ATPase by Proteomic Technique and Pan Antipalmitoylation Antibody.	26865113
Caballero MC et al.	2016	Identification of new palmitoylated proteins in Toxoplasma gondii.	26825284
Upadhyay S et al.	2016	Interactions between Melanin Enzymes and Their Atypical Recruitment to the Secretory Pathway by Palmitoylation.	27879337
Edmonds MJ et al.	2017	Analysis of the brain palmitoyl-proteome using both acyl-biotin exchange and acyl-resin-assisted capture methods.	28607426
Shen LF et al.	2017	Role of S-Palmitoylation by ZDHHC13 in Mitochondrial function and Metabolism in Liver.	28526873
Sobocińska J et al.	2018	Lipopolysaccharide Upregulates Palmitoylated Enzymes of the Phosphatidylinositol Cycle: An Insight from Proteomic Studies.	29217618
Collins MO et al.	2017	Global, site-specific analysis of neuronal protein S-acylation.	28680068
Thinon E et al.	2016	Bioorthogonal Chemical Reporters for Monitoring Unsaturated Fatty-Acylated Proteins.	27350074
Thinon E et al.	2018	Selective Enrichment and Direct Analysis of Protein S-Palmitoylation Sites.	29575903
Zhang X et al.	2018	Ultradeep Palmitoylomics Enabled by Dithiodipyridine-Functionalized Magnetic Nanoparticles.	29660268
Won SJ et al.	2018	Temporal Profiling Establishes a Dynamic S-Palmitoylation Cycle.	29733200
Dumoulin A et al.	2018	S-palmitoylation Is Required for the Control of Growth Cone Morphology of DRG Neurons by CNP-Induced cGMP Signaling.	30319353
Wang Z et al.	2018	Proteomic Analysis of S-Palmitoylated Proteins in Ocular Lens Reveals Palmitoylation of AQP5 and MP20.	30489624
Wang J et al.	2019	DHHC4 and DHHC5 Facilitate Fatty Acid Uptake by Palmitoylating and Targeting CD36 to the Plasma Membrane.	30605677
Strassburger K et al.	2019	Drosophila ZDHHC8 palmitoylates scribble and Ras64B and controls growth and viability.	30735487
Zhou B et al.	2019	Low-background Acyl-biotinyl Exchange Largely Eliminates the Co-isolation of Non-S-acylated Proteins and Enables Deep S-acylproteomic Analysis.	31251020
Zaręba-Kozioł M et al.	2019	Stress-induced changes in the S-palmitoylation and S-nitrosylation of synaptic proteins.	31311849
Wegleiter T et al.	2019	Palmitoylation of BMPR1a regulates neural stem cell fate.	31772009
Morrison E et al.	2020	Dynamic palmitoylation events following T-cell receptor signaling.	32651440
Mariscal J et al.	2020	Comprehensive palmitoyl-proteomic analysis identifies distinct protein signatures for large and small cancer-derived extracellular vesicles.	32944167
Gorenberg EL et al.	2022	Identification of substrates of palmitoyl protein thioesterase 1 highlights roles of depalmitoylation in disulfide bond formation and synaptic function.	35358180
Uzbekova S et al.	2021	Protein Palmitoylation in Bovine Ovarian Follicle.	34769186
Miles MR et al.	2021	Global identification of S-palmitoylated proteins and detection of palmitoylating (DHHC) enzymes in heart.	33636221
Pradhan AJ et al.	2021	Protein acylation by saturated very long chain fatty acids and endocytosis are involved in necroptosis.	33848465
Ripamonti M et al.	2021	Structural and functional analysis of LIM domain-dependent recruitment of paxillin to αvβ3 integrin-positive focal adhesions.	33782527
Zaręba-Kozioł M et al.	2021	S-Palmitoylation of Synaptic Proteins as a Novel Mechanism Underlying Sex-Dependent Differences in Neuronal Plasticity.	34200797
Ziemlińska E et al.	2021	Palm Oil-Rich Diet Affects Murine Liver Proteome and <i>S</i>-Palmitoylome.	34884899
Gao J et al.	2022	Proteome-wide identification of palmitoylated proteins in mouse testis.	35477839