SwissPalm

Q86XX4 FRAS1_HUMAN

General info Cross-references Sequences Orthologs Ortholog sequences Predictions Palmitoyl-proteomes References

Palmitoyl-proteomes

2/22 articles for human
1 ortholog

Palmitoyl-proteome experiments

Validation experiments

0 experiment
0 ortholog

Curated sites & Enzymes

0 site from validation experiments^*
0 site from palmitoyl-proteomes^*
No PAT known
No APT known
^*In main isoform only

Predictions

Predicted, Not validated

12 cysteines in main isoform

Predictions

Protein general information from UniProt

Protein names

Extracellular matrix organizing protein FRAS1; Fraser syndrome 1 protein

Subcellular location

Cell membrane (By similarity)

Isoforms & protein length

Isoform 1 (main): 4008 aa; Isoform 2 : 4012 aa; Isoform 4 : 737 aa; Isoform 5 : 1976 aa; Isoform 6 : 809 aa

Known functions

Involved in extracellular matrix organization (By similarity). Required for the regulation of epidermal-basement membrane adhesion responsible for proper organogenesis during embryonic development (By similarity). Involved in brain organization and function (By similarity).

Cross-references

Source	Identifiers
UniProt gene names	FRAS1, KIAA1500
UniProt secondary AC	A2RRR8, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228
Refseq protein ID	NP_001159605.1, NP_079350.5
IPI ID	IPI00455316, IPI00455318, IPI00455319, IPI00455320, IPI00943593, IPI00967051, IPI00873539, IPI00747193, IPI00455317, IPI00410197, IPI00410119, IPI00329327

Source	Identifiers
Ensembl protein	ENSP00000422834, ENSP00000264895, ENSP00000264899, ENSP00000326330
Ensembl gene	ENSG00000138759

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Isoform sequence alignment

Tip: Hover over an amino acid to display its position!

Orthologs

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UniProt AC	UniProt ID	Orthology source	Organism	Gene names	Protein name	Palmitome articles	Techniques	Predicted
Q80T14	FRAS1_MOUSE	InParanoid, OrthoDB, OMA, MetaPhors	M. musculus	Fras1, Kiaa1500	Extracellular matrix organizing protein FRAS1	1/23	2	Yes
J9P6T8	J9P6T8_CANLF	InParanoid, OMA	C. familiaris	FRAS1	Fraser extracellular matrix complex subunit 1	0/1	0	Yes
F1N740	F1N740_BOVIN	InParanoid, OMA	B. taurus	FRAS1	Fraser extracellular matrix complex subunit 1	0/2	0	Yes
O74853	FAP1H_SCHPO	MetaPhors	S. pombe	fap1, SPCC18.03	FKBP12-associated protein 1 homolog	0/1	0	Yes
F1M3H3	F1M3H3_RAT	InParanoid, OMA	R. norvegicus	Fras1	Fraser extracellular matrix complex subunit 1	0/3	0	Yes

Ortholog sequence alignment (CLUSTALW)

Cysteine summary and predictions

Pos in alignment	28	46	49	51	58	63	68	83	84	87	95	113	116	118
Subcell. location	E	E	E	E	E	E	E	E	E	E	E	E	E	E
Disulfide	no	no	no	no	no	no	no	no	no	no	no	no	no	no
PSIPRED v.4.02 prediction	coil	coil	coil	strand	coil	strand	coil	strand	coil	coil	strand	coil	strand	coil
UniProt secondary structure	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Pos in isoform 1 [Main] CSS-Palm 4.0 PalmPred	Cys²⁸	Cys⁴⁶	Cys⁴⁹	Cys⁵¹	Cys⁵⁸	Cys⁶³	Cys⁶⁸	Cys⁸³ HC	Cys⁸⁴ LC	Cys⁸⁷	Cys⁹⁵	Cys¹¹³	Cys¹¹⁶	Cys¹¹⁸ MC
Pos in isoform 2 CSS-Palm 4.0 PalmPred	Cys²⁸	Cys⁴⁶	Cys⁴⁹	Cys⁵¹	Cys⁵⁸	Cys⁶³	Cys⁶⁸	Cys⁸³ HC	Cys⁸⁴ LC	Cys⁸⁷	Cys⁹⁵	Cys¹¹³	Cys¹¹⁶	Cys¹¹⁸ MC
Pos in isoform 4 CSS-Palm 4.0 PalmPred	Cys²⁸	Cys⁴⁶	Cys⁴⁹	Cys⁵¹	Cys⁵⁸	Cys⁶³	Cys⁶⁸	Cys⁸³ HC	Cys⁸⁴ LC	Cys⁸⁷	Cys⁹⁵	Cys¹¹³	Cys¹¹⁶	Cys¹¹⁸ MC
Pos in isoform 5 CSS-Palm 4.0 PalmPred	Cys²⁸	Cys⁴⁶	Cys⁴⁹	Cys⁵¹	Cys⁵⁸	Cys⁶³	Cys⁶⁸	Cys⁸³ HC	Cys⁸⁴ LC	Cys⁸⁷	Cys⁹⁵	Cys¹¹³	Cys¹¹⁶	Cys¹¹⁸ MC
Pos in isoform 6 CSS-Palm 4.0 PalmPred	Cys²⁸	Cys⁴⁶	Cys⁴⁹	Cys⁵¹	Cys⁵⁸	Cys⁶³	Cys⁶⁸	Cys⁸³ HC	Cys⁸⁴ LC	Cys⁸⁷	Cys⁹⁵	Cys¹¹³	Cys¹¹⁶	Cys¹¹⁸ MC

Pos in alignment	125	130	135	148	149	152	159	177	180	182	189	194	199	212
Subcell. location	E	E	E	E	E	E	E	E	E	E	E	E	E	E
Disulfide	no	no	no	no	no	no	no	no	no	no	no	no	no	no
PSIPRED v.4.02 prediction	strand	coil	coil	strand	strand	coil	strand	coil	strand	strand	strand	coil	strand	strand
UniProt secondary structure	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Pos in isoform 1 [Main] CSS-Palm 4.0 PalmPred	Cys¹²⁵	Cys¹³⁰ LC	Cys¹³⁵	Cys¹⁴⁸ HC	Cys¹⁴⁹	Cys¹⁵²	Cys¹⁵⁹	Cys¹⁷⁷	Cys¹⁸⁰	Cys¹⁸²	Cys¹⁸⁹ MC	Cys¹⁹⁴	Cys¹⁹⁹	Cys²¹² HC
Pos in isoform 2 CSS-Palm 4.0 PalmPred	Cys¹²⁵	Cys¹³⁰ LC	Cys¹³⁵	Cys¹⁴⁸ HC	Cys¹⁴⁹	Cys¹⁵²	Cys¹⁵⁹	Cys¹⁷⁷	Cys¹⁸⁰	Cys¹⁸²	Cys¹⁸⁹ MC	Cys¹⁹⁴	Cys¹⁹⁹	Cys²¹² HC
Pos in isoform 4 CSS-Palm 4.0 PalmPred	Cys¹²⁵	Cys¹³⁰ LC	Cys¹³⁵	Cys¹⁴⁸ HC	Cys¹⁴⁹	Cys¹⁵²	Cys¹⁵⁹	Cys¹⁷⁷	Cys¹⁸⁰	Cys¹⁸²	Cys¹⁸⁹ MC	Cys¹⁹⁴	Cys¹⁹⁹	Cys²¹² HC
Pos in isoform 5 CSS-Palm 4.0 PalmPred	Cys¹²⁵	Cys¹³⁰ LC	Cys¹³⁵	Cys¹⁴⁸ HC	Cys¹⁴⁹	Cys¹⁵²	Cys¹⁵⁹	Cys¹⁷⁷	Cys¹⁸⁰	Cys¹⁸²	Cys¹⁸⁹ MC	Cys¹⁹⁴	Cys¹⁹⁹	Cys²¹² HC
Pos in isoform 6 CSS-Palm 4.0 PalmPred	Cys¹²⁵	Cys¹³⁰ LC	Cys¹³⁵	Cys¹⁴⁸ HC	Cys¹⁴⁹	Cys¹⁵²	Cys¹⁵⁹	Cys¹⁷⁷	Cys¹⁸⁰	Cys¹⁸²	Cys¹⁸⁹ MC	Cys¹⁹⁴	Cys¹⁹⁹	Cys²¹² HC

Pos in alignment	213	216	221	239	242	244	251	256	261	274	275	278	285	303
Subcell. location	E	E	E	E	E	E	E	E	E	E	E	E	E	E
Disulfide	no	no	no	no	no	no	no	no	no	no	no	no	no	no
PSIPRED v.4.02 prediction	coil	coil	strand	coil	strand	coil	strand	strand	coil	strand	coil	coil	coil	coil
UniProt secondary structure	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Pos in isoform 1 [Main] CSS-Palm 4.0 PalmPred	Cys²¹³ HC	Cys²¹⁶	Cys²²¹	Cys²³⁹	Cys²⁴²	Cys²⁴⁴	Cys²⁵¹	Cys²⁵⁶	Cys²⁶¹	Cys²⁷⁴ HC	Cys²⁷⁵	Cys²⁷⁸	Cys²⁸⁵	Cys³⁰³
Pos in isoform 2 CSS-Palm 4.0 PalmPred	Cys²¹³ HC	Cys²¹⁶	Cys²²¹	Cys²³⁹	Cys²⁴²	Cys²⁴⁴	Cys²⁵¹	Cys²⁵⁶	Cys²⁶¹	Cys²⁷⁴ HC	Cys²⁷⁵	Cys²⁷⁸	Cys²⁸⁵	Cys³⁰³
Pos in isoform 4 CSS-Palm 4.0 PalmPred	Cys²¹³ HC	Cys²¹⁶	Cys²²¹	Cys²³⁹	Cys²⁴²	Cys²⁴⁴	Cys²⁵¹	Cys²⁵⁶	Cys²⁶¹	Cys²⁷⁴ HC	Cys²⁷⁵	Cys²⁷⁸	Cys²⁸⁵	Cys³⁰³
Pos in isoform 5 CSS-Palm 4.0 PalmPred	Cys²¹³ HC	Cys²¹⁶	Cys²²¹	Cys²³⁹	Cys²⁴²	Cys²⁴⁴	Cys²⁵¹	Cys²⁵⁶	Cys²⁶¹	Cys²⁷⁴ HC	Cys²⁷⁵	Cys²⁷⁸	Cys²⁸⁵	Cys³⁰³
Pos in isoform 6 CSS-Palm 4.0 PalmPred	Cys²¹³ HC	Cys²¹⁶	Cys²²¹	Cys²³⁹	Cys²⁴²	Cys²⁴⁴	Cys²⁵¹	Cys²⁵⁶	Cys²⁶¹	Cys²⁷⁴ HC	Cys²⁷⁵	Cys²⁷⁸	Cys²⁸⁵	Cys³⁰³

Pos in alignment	306	308	315	320	325	338	339	342	349	379	382	384	391	396
Subcell. location	E	E	E	E	E	E	E	E	E	E	E	E	E	E
Disulfide	no	no	no	no	no	no	no	no	no	no	no	no	no	no
PSIPRED v.4.02 prediction	strand	coil	strand	strand	coil	strand	coil	coil	strand	strand	coil	coil	coil	coil
UniProt secondary structure	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Pos in isoform 1 [Main] CSS-Palm 4.0 PalmPred	Cys³⁰⁶	Cys³⁰⁸ HC	Cys³¹⁵	Cys³²⁰	Cys³²⁵	Cys³³⁸ HC	Cys³³⁹ HC	Cys³⁴²	Cys³⁴⁹	Cys³⁷⁹	Cys³⁸²	Cys³⁸⁴	Cys³⁹¹	Cys³⁹⁶
Pos in isoform 2 CSS-Palm 4.0 PalmPred	Cys³⁰⁶	Cys³⁰⁸ HC	Cys³¹⁵	Cys³²⁰	Cys³²⁵	Cys³³⁸ HC	Cys³³⁹ HC	Cys³⁴²	Cys³⁴⁹	Cys³⁷⁹	Cys³⁸²	Cys³⁸⁴	Cys³⁹¹	Cys³⁹⁶
Pos in isoform 4 CSS-Palm 4.0 PalmPred	Cys³⁰⁶	Cys³⁰⁸ HC	Cys³¹⁵	Cys³²⁰	Cys³²⁵	Cys³³⁸ HC	Cys³³⁹ HC	Cys³⁴²	Cys³⁴⁹	Cys³⁷⁹	Cys³⁸²	Cys³⁸⁴	Cys³⁹¹	Cys³⁹⁶
Pos in isoform 5 CSS-Palm 4.0 PalmPred	Cys³⁰⁶	Cys³⁰⁸ HC	Cys³¹⁵	Cys³²⁰	Cys³²⁵	Cys³³⁸ HC	Cys³³⁹ HC	Cys³⁴²	Cys³⁴⁹	Cys³⁷⁹	Cys³⁸²	Cys³⁸⁴	Cys³⁹¹	Cys³⁹⁶
Pos in isoform 6 CSS-Palm 4.0 PalmPred	Cys³⁰⁶	Cys³⁰⁸ HC	Cys³¹⁵	Cys³²⁰	Cys³²⁵	Cys³³⁸ HC	Cys³³⁹ HC	Cys³⁴²	Cys³⁴⁹	Cys³⁷⁹	Cys³⁸²	Cys³⁸⁴	Cys³⁹¹	Cys³⁹⁶

Pos in alignment	399	412	413	416	421	425	428	435	438	450	454	465	468	472
Subcell. location	E	E	E	E	E	E	E	E	E	E	E	E	E	E
Disulfide	no	no	no	no	no	no	no	no	no	no	no	no	no	no
PSIPRED v.4.02 prediction	coil	strand	coil	coil	coil	coil	strand	coil	coil	strand	coil	strand	coil	coil
UniProt secondary structure	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Pos in isoform 1 [Main] CSS-Palm 4.0 PalmPred	Cys³⁹⁹ LC	Cys⁴¹² HC	Cys⁴¹³ MC	Cys⁴¹⁶	Cys⁴²¹ HC	Cys⁴²⁵	Cys⁴²⁸	Cys⁴³⁵	Cys⁴³⁸	Cys⁴⁵⁰ LC	Cys⁴⁵⁴	Cys⁴⁶⁵	Cys⁴⁶⁸	Cys⁴⁷²
Pos in isoform 2 CSS-Palm 4.0 PalmPred	Cys³⁹⁹ LC	Cys⁴¹² HC	Cys⁴¹³ MC	Cys⁴¹⁶	Cys⁴²¹ HC	Cys⁴²⁵	Cys⁴²⁸	Cys⁴³⁵	Cys⁴³⁸	Cys⁴⁵⁰ LC	Cys⁴⁵⁴	Cys⁴⁶⁵	Cys⁴⁶⁸	Cys⁴⁷²
Pos in isoform 4 CSS-Palm 4.0 PalmPred	Cys³⁹⁹ LC	Cys⁴¹² HC	Cys⁴¹³ MC	Cys⁴¹⁶	Cys⁴²¹ HC	Cys⁴²⁵	Cys⁴²⁸	Cys⁴³⁵	Cys⁴³⁸	Cys⁴⁵⁰ LC	Cys⁴⁵⁴	Cys⁴⁶⁵	Cys⁴⁶⁸	Cys⁴⁷²
Pos in isoform 5 CSS-Palm 4.0 PalmPred	Cys³⁹⁹ LC	Cys⁴¹² HC	Cys⁴¹³ MC	Cys⁴¹⁶	Cys⁴²¹ HC	Cys⁴²⁵	Cys⁴²⁸	Cys⁴³⁵	Cys⁴³⁸	Cys⁴⁵⁰ LC	Cys⁴⁵⁴	Cys⁴⁶⁵	Cys⁴⁶⁸	Cys⁴⁷²
Pos in isoform 6 CSS-Palm 4.0 PalmPred	Cys³⁹⁹ LC	Cys⁴¹² HC	Cys⁴¹³ MC	Cys⁴¹⁶	Cys⁴²¹ HC	Cys⁴²⁵	Cys⁴²⁸	Cys⁴³⁵	Cys⁴³⁸	Cys⁴⁵⁰ LC	Cys⁴⁵⁴	Cys⁴⁶⁵	Cys⁴⁶⁸	Cys⁴⁷²

Pos in alignment	475	481	484	495	499	510	513	517	520	528	531	543	547	558
Subcell. location	E	E	E	E	E	E	E	E	E	E	E	E	E	E
Disulfide	no	no	no	no	no	no	no	no	no	no	no	no	no	no
PSIPRED v.4.02 prediction	strand	strand	coil	strand	coil	strand	coil	coil	coil	coil	coil	strand	coil	strand
UniProt secondary structure	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Pos in isoform 1 [Main] CSS-Palm 4.0 PalmPred	Cys⁴⁷⁵	Cys⁴⁸¹	Cys⁴⁸⁴	Cys⁴⁹⁵	Cys⁴⁹⁹	Cys⁵¹⁰ MC	Cys⁵¹³	Cys⁵¹⁷	Cys⁵²⁰	Cys⁵²⁸	Cys⁵³¹	Cys⁵⁴³	Cys⁵⁴⁷	Cys⁵⁵⁸
Pos in isoform 2 CSS-Palm 4.0 PalmPred	Cys⁴⁷⁵	Cys⁴⁸¹	Cys⁴⁸⁴	Cys⁴⁹⁵	Cys⁴⁹⁹	Cys⁵¹⁰ MC	Cys⁵¹³	Cys⁵¹⁷	Cys⁵²⁰	Cys⁵²⁸	Cys⁵³¹	Cys⁵⁴³	Cys⁵⁴⁷	Cys⁵⁵⁸
Pos in isoform 4 CSS-Palm 4.0 PalmPred	Cys⁴⁷⁵	Cys⁴⁸¹	Cys⁴⁸⁴	Cys⁴⁹⁵	Cys⁴⁹⁹	Cys⁵¹⁰ MC	Cys⁵¹³	Cys⁵¹⁷	Cys⁵²⁰	Cys⁵²⁸	Cys⁵³¹	Cys⁵⁴³	Cys⁵⁴⁷	Cys⁵⁵⁸
Pos in isoform 5 CSS-Palm 4.0 PalmPred	Cys⁴⁷⁵	Cys⁴⁸¹	Cys⁴⁸⁴	Cys⁴⁹⁵	Cys⁴⁹⁹	Cys⁵¹⁰ MC	Cys⁵¹³	Cys⁵¹⁷	Cys⁵²⁰	Cys⁵²⁸	Cys⁵³¹	Cys⁵⁴³	Cys⁵⁴⁷	Cys⁵⁵⁸
Pos in isoform 6 CSS-Palm 4.0 PalmPred	Cys⁴⁷⁵	Cys⁴⁸¹	Cys⁴⁸⁴	Cys⁴⁹⁵	Cys⁴⁹⁹	Cys⁵¹⁰ MC	Cys⁵¹³	Cys⁵¹⁷	Cys⁵²⁰	Cys⁵²⁸	Cys⁵³¹	Cys⁵⁴³	Cys⁵⁴⁷	Cys⁵⁵⁸

Pos in alignment	561	565	568	575	578	589	593	605	608	612	615	623	626	637
Subcell. location	E	E	E	E	E	E	E	E	E	E	E	E	E	E
Disulfide	no	no	no	no	no	no	no	no	no	no	no	no	no	no
PSIPRED v.4.02 prediction	coil	coil	coil	strand	coil	strand	coil	strand	coil	coil	coil	coil	coil	strand
UniProt secondary structure	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Pos in isoform 1 [Main] CSS-Palm 4.0 PalmPred	Cys⁵⁶¹	Cys⁵⁶⁵	Cys⁵⁶⁸ MC	Cys⁵⁷⁵ LC	Cys⁵⁷⁸	Cys⁵⁸⁹	Cys⁵⁹³ MC	Cys⁶⁰⁵	Cys⁶⁰⁸ LC	Cys⁶¹²	Cys⁶¹⁵ LC	Cys⁶²³	Cys⁶²⁶	Cys⁶³⁷
Pos in isoform 2 CSS-Palm 4.0 PalmPred	Cys⁵⁶¹	Cys⁵⁶⁵	Cys⁵⁶⁸ MC	Cys⁵⁷⁵ LC	Cys⁵⁷⁸	Cys⁵⁸⁹	Cys⁵⁹³ MC	Cys⁶⁰⁵	Cys⁶⁰⁸ LC	Cys⁶¹²	Cys⁶¹⁵ LC	Cys⁶²³	Cys⁶²⁶	Cys⁶³⁷
Pos in isoform 4 CSS-Palm 4.0 PalmPred	Cys⁵⁶¹	Cys⁵⁶⁵	Cys⁵⁶⁸ MC	Cys⁵⁷⁵ LC	Cys⁵⁷⁸	Cys⁵⁸⁹	Cys⁵⁹³ MC	Cys⁶⁰⁵	Cys⁶⁰⁸ LC	Cys⁶¹²	Cys⁶¹⁵ LC	Cys⁶²³	Cys⁶²⁶	Cys⁶³⁷
Pos in isoform 5 CSS-Palm 4.0 PalmPred	Cys⁵⁶¹	Cys⁵⁶⁵	Cys⁵⁶⁸ MC	Cys⁵⁷⁵ LC	Cys⁵⁷⁸	Cys⁵⁸⁹	Cys⁵⁹³ MC	Cys⁶⁰⁵	Cys⁶⁰⁸ LC	Cys⁶¹²	Cys⁶¹⁵ LC	Cys⁶²³	Cys⁶²⁶	Cys⁶³⁷
Pos in isoform 6 CSS-Palm 4.0 PalmPred	Cys⁵⁶¹	Cys⁵⁶⁵	Cys⁵⁶⁸ MC	Cys⁵⁷⁵ LC	Cys⁵⁷⁸	Cys⁵⁸⁹	Cys⁵⁹³ MC	Cys⁶⁰⁵	Cys⁶⁰⁸ LC	Cys⁶¹²	Cys⁶¹⁵ LC	Cys⁶²³	Cys⁶²⁶	Cys⁶³⁷

Pos in alignment	641	652	655	659	662	670	673	695	699	711	714	718	721	729
Subcell. location	E	E	E	E	E	E	E	E	E	E	E	E	E	E
Disulfide	no	no	no	no	no	no	no	no	no	no	no	no	no	no
PSIPRED v.4.02 prediction	coil	strand	coil	coil	coil	coil	coil	strand	coil	strand	coil	coil	coil	coil
UniProt secondary structure	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Pos in isoform 1 [Main] CSS-Palm 4.0 PalmPred	Cys⁶⁴¹	Cys⁶⁵²	Cys⁶⁵⁵	Cys⁶⁵⁹ MC	Cys⁶⁶²	Cys⁶⁷⁰	Cys⁶⁷³ MC	Cys⁶⁹⁵	Cys⁶⁹⁹	Cys⁷¹¹	Cys⁷¹⁴	Cys⁷¹⁸	Cys⁷²¹	Cys⁷²⁹
Pos in isoform 2 CSS-Palm 4.0 PalmPred	Cys⁶⁴¹	Cys⁶⁵²	Cys⁶⁵⁵	Cys⁶⁵⁹ MC	Cys⁶⁶²	Cys⁶⁷⁰	Cys⁶⁷³ MC	Cys⁶⁹⁵	Cys⁶⁹⁹	Cys⁷¹¹	Cys⁷¹⁴	Cys⁷¹⁸	Cys⁷²¹	Cys⁷²⁹
Pos in isoform 4 CSS-Palm 4.0 PalmPred	Cys⁶⁴¹	Cys⁶⁵²	Cys⁶⁵⁵	Cys⁶⁵⁹ MC	Cys⁶⁶²	Cys⁶⁷⁰	Cys⁶⁷³ MC	Cys⁶⁹⁵	Cys⁶⁹⁹	Cys⁷¹¹
Pos in isoform 5 CSS-Palm 4.0 PalmPred	Cys⁶⁴¹	Cys⁶⁵²	Cys⁶⁵⁵	Cys⁶⁵⁹ MC	Cys⁶⁶²	Cys⁶⁷⁰	Cys⁶⁷³ MC	Cys⁶⁹⁵	Cys⁶⁹⁹	Cys⁷¹¹	Cys⁷¹⁴	Cys⁷¹⁸	Cys⁷²¹	Cys⁷²⁹
Pos in isoform 6 CSS-Palm 4.0 PalmPred	Cys⁶⁴¹	Cys⁶⁵²	Cys⁶⁵⁵	Cys⁶⁵⁹ MC	Cys⁶⁶²	Cys⁶⁷⁰	Cys⁶⁷³ MC	Cys⁶⁹⁵	Cys⁶⁹⁹	Cys⁷¹¹	Cys⁷¹⁴	Cys⁷¹⁸	Cys⁷²¹	Cys⁷²⁹

Pos in alignment	732	743	747	758	761	765	768	776	779	790	794	806	809	813
Subcell. location	E	E	E	E	E	E	E	E	E	E	E	E	E	E
Disulfide	no	no	no	no	no	no	no	no	no	no	no	no	no	no
PSIPRED v.4.02 prediction	coil	strand	coil	strand	coil	coil	coil	coil	coil	strand	coil	strand	coil	coil
UniProt secondary structure	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Pos in isoform 1 [Main] CSS-Palm 4.0 PalmPred	Cys⁷³²	Cys⁷⁴³	Cys⁷⁴⁷	Cys⁷⁵⁸ MC	Cys⁷⁶¹	Cys⁷⁶⁵	Cys⁷⁶⁸	Cys⁷⁷⁶	Cys⁷⁷⁹	Cys⁷⁹⁰	Cys⁷⁹⁴	Cys⁸⁰⁶	Cys⁸⁰⁹	Cys⁸¹³
Pos in isoform 2 CSS-Palm 4.0 PalmPred	Cys⁷³²	Cys⁷⁴³	Cys⁷⁴⁷	Cys⁷⁵⁸ MC	Cys⁷⁶¹	Cys⁷⁶⁵	Cys⁷⁶⁸	Cys⁷⁷⁶	Cys⁷⁷⁹	Cys⁷⁹⁰	Cys⁷⁹⁴	Cys⁸⁰⁶	Cys⁸⁰⁹	Cys⁸¹³
Pos in isoform 4 CSS-Palm 4.0 PalmPred			Cys⁷¹⁹
Pos in isoform 5 CSS-Palm 4.0 PalmPred	Cys⁷³²	Cys⁷⁴³	Cys⁷⁴⁷	Cys⁷⁵⁸ MC	Cys⁷⁶¹	Cys⁷⁶⁵	Cys⁷⁶⁸	Cys⁷⁷⁶	Cys⁷⁷⁹	Cys⁷⁹⁰	Cys⁷⁹⁴	Cys⁸⁰⁶	Cys⁸⁰⁹	Cys⁸¹³
Pos in isoform 6 CSS-Palm 4.0 PalmPred	Cys⁷³²	Cys⁷⁴³	Cys⁷⁴⁷	Cys⁷⁵⁸ MC	Cys⁷⁶¹	Cys⁷⁶⁵	Cys⁷⁶⁸	Cys⁷⁷⁶	Cys⁷⁷⁹	Cys⁷⁹⁰	Cys⁷⁹⁴	Cys⁸⁰⁶

Pos in alignment	816	827	830	842	846	857	860	864	867	875	878	890	894	906
Subcell. location	E	E	E	E	E	E	E	E	E	E	E	E	E	E
Disulfide	no	no	no	no	no	no	no	no	no	no	no	no	no	no
PSIPRED v.4.02 prediction	coil	coil	coil	strand	coil	strand	coil	coil	coil	strand	coil	strand	coil	strand
UniProt secondary structure	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Pos in isoform 1 [Main] CSS-Palm 4.0 PalmPred	Cys⁸¹⁶	Cys⁸²⁷	Cys⁸³⁰	Cys⁸⁴²	Cys⁸⁴⁶	Cys⁸⁵⁷	Cys⁸⁶⁰	Cys⁸⁶⁴	Cys⁸⁶⁷	Cys⁸⁷⁵ LC	Cys⁸⁷⁸	Cys⁸⁹⁰	Cys⁸⁹⁴	Cys⁹⁰⁶
Pos in isoform 2 CSS-Palm 4.0 PalmPred	Cys⁸¹⁶	Cys⁸²⁷	Cys⁸³⁰	Cys⁸⁴²	Cys⁸⁴⁶	Cys⁸⁵⁷	Cys⁸⁶⁰	Cys⁸⁶⁴	Cys⁸⁶⁷	Cys⁸⁷⁵ LC	Cys⁸⁷⁸	Cys⁸⁹⁰	Cys⁸⁹⁴	Cys⁹⁰⁶
Pos in isoform 4 CSS-Palm 4.0 PalmPred		Cys⁷²⁹
Pos in isoform 5 CSS-Palm 4.0 PalmPred	Cys⁸¹⁶	Cys⁸²⁷	Cys⁸³⁰	Cys⁸⁴²	Cys⁸⁴⁶	Cys⁸⁵⁷	Cys⁸⁶⁰	Cys⁸⁶⁴	Cys⁸⁶⁷	Cys⁸⁷⁵ LC	Cys⁸⁷⁸	Cys⁸⁹⁰	Cys⁸⁹⁴	Cys⁹⁰⁶
Pos in isoform 6 CSS-Palm 4.0 PalmPred

Pos in alignment	909	913	916	922	925	937	942	955	958	962	965	973	976	987
Subcell. location	E	E	E	E	E	E	E	E	E	E	E	E	E	E
Disulfide	no	no	no	no	no	no	no	no	no	no	no	no	no	no
PSIPRED v.4.02 prediction	coil	coil	coil	strand	coil	strand	coil	strand	coil	coil	coil	coil	coil	strand
UniProt secondary structure	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Pos in isoform 1 [Main] CSS-Palm 4.0 PalmPred	Cys⁹⁰⁹ LC	Cys⁹¹³	Cys⁹¹⁶	Cys⁹²²	Cys⁹²⁵	Cys⁹³⁷	Cys⁹⁴²	Cys⁹⁵⁵	Cys⁹⁵⁸ LC	Cys⁹⁶²	Cys⁹⁶⁵ LC	Cys⁹⁷³	Cys⁹⁷⁶	Cys⁹⁸⁷
Pos in isoform 2 CSS-Palm 4.0 PalmPred	Cys⁹⁰⁹ LC	Cys⁹¹³	Cys⁹¹⁶	Cys⁹²²	Cys⁹²⁵	Cys⁹³⁷	Cys⁹⁴²	Cys⁹⁵⁵	Cys⁹⁵⁸ LC	Cys⁹⁶²	Cys⁹⁶⁵ LC	Cys⁹⁷³	Cys⁹⁷⁶	Cys⁹⁸⁷
Pos in isoform 4 CSS-Palm 4.0 PalmPred
Pos in isoform 5 CSS-Palm 4.0 PalmPred	Cys⁹⁰⁹ LC	Cys⁹¹³	Cys⁹¹⁶	Cys⁹²²	Cys⁹²⁵	Cys⁹³⁷	Cys⁹⁴²	Cys⁹⁵⁵	Cys⁹⁵⁸ LC	Cys⁹⁶²	Cys⁹⁶⁵ LC	Cys⁹⁷³	Cys⁹⁷⁶	Cys⁹⁸⁷
Pos in isoform 6 CSS-Palm 4.0 PalmPred

Pos in alignment	991	1002	1005	1009	1012	1018	1021	1032	1036	1049	1052	1056	1059	1065
Subcell. location	E	E	E	E	E	E	E	E	E	E	E	E	E	E
Disulfide	no	no	no	no	no	no	no	no	no	no	no	no	no	no
PSIPRED v.4.02 prediction	coil	strand	coil	coil	coil	coil	coil	strand	coil	strand	coil	coil	coil	strand
UniProt secondary structure	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
Pos in isoform 1 [Main] CSS-Palm 4.0 PalmPred	Cys⁹⁹¹	Cys¹⁰⁰²	Cys¹⁰⁰⁵ HC	Cys¹⁰⁰⁹	Cys¹⁰¹²	Cys¹⁰¹⁸	Cys¹⁰²¹	Cys¹⁰³²	Cys¹⁰³⁶	Cys¹⁰⁴⁹ HC	Cys¹⁰⁵² MC	Cys¹⁰⁵⁶	Cys¹⁰⁵⁹	Cys¹⁰⁶⁵
Pos in isoform 2 CSS-Palm 4.0 PalmPred	Cys⁹⁹¹	Cys¹⁰⁰²	Cys¹⁰⁰⁵ HC	Cys¹⁰⁰⁹	Cys¹⁰¹²	Cys¹⁰¹⁸	Cys¹⁰²¹	Cys¹⁰³²	Cys¹⁰³⁶	Cys¹⁰⁴⁹ HC	Cys¹⁰⁵² MC	Cys¹⁰⁵⁶	Cys¹⁰⁵⁹	Cys¹⁰⁶⁵
Pos in isoform 4 CSS-Palm 4.0 PalmPred
Pos in isoform 5 CSS-Palm 4.0 PalmPred	Cys⁹⁹¹	Cys¹⁰⁰²	Cys¹⁰⁰⁵ HC	Cys¹⁰⁰⁹	Cys¹⁰¹²	Cys¹⁰¹⁸	Cys¹⁰²¹	Cys¹⁰³²	Cys¹⁰³⁶	Cys¹⁰⁴⁹ HC	Cys¹⁰⁵² MC	Cys¹⁰⁵⁶	Cys¹⁰⁵⁹	Cys¹⁰⁶⁵
Pos in isoform 6 CSS-Palm 4.0 PalmPred

Pos in alignment	1068	1079	1083	1096	1882	2589	2629	2710	2753	2836	2870	2955	2990	3081
Subcell. location	E	E	E	E	E	E	E	E	E	E	E	E	E	E
Disulfide	no	no	no	no	no	no	no	no	no	no	no	no	no	no
PSIPRED v.4.02 prediction	coil	strand	coil	strand	strand	strand
UniProt secondary structure	NA	NA	NA	NA	NA	NA
Pos in isoform 1 [Main] CSS-Palm 4.0 PalmPred	Cys¹⁰⁶⁸	Cys¹⁰⁷⁹	Cys¹⁰⁸³	Cys¹⁰⁹⁶	Cys¹⁸⁸²	Cys²⁵⁸⁹	Cys²⁶²⁵	Cys²⁷⁰⁶	Cys²⁷⁴⁹	Cys²⁸³²	Cys²⁸⁶⁶	Cys²⁹⁵¹	Cys²⁹⁸⁶	Cys³⁰⁷⁷
Pos in isoform 2 CSS-Palm 4.0 PalmPred	Cys¹⁰⁶⁸	Cys¹⁰⁷⁹	Cys¹⁰⁸³	Cys¹⁰⁹⁶	Cys¹⁸⁸²	Cys²⁵⁸⁹	Cys²⁶²⁹	Cys²⁷¹⁰	Cys²⁷⁵³	Cys²⁸³⁶	Cys²⁸⁷⁰	Cys²⁹⁵⁵	Cys²⁹⁹⁰	Cys³⁰⁸¹
Pos in isoform 4 CSS-Palm 4.0 PalmPred
Pos in isoform 5 CSS-Palm 4.0 PalmPred	Cys¹⁰⁶⁸	Cys¹⁰⁷⁹	Cys¹⁰⁸³	Cys¹⁰⁹⁶	Cys¹⁸⁸²
Pos in isoform 6 CSS-Palm 4.0 PalmPred

Pos in alignment	3198	3202	3216	3275	3304	3378	3437	3454	3617	3635	3669	3727	3752	3924
Subcell. location	E	E	E	E	E	E	E	E	E	E	E	E	E	T
Disulfide	no	no	no	no	no	no	no	no	no	no	no	no	no	no
PSIPRED v.4.02 prediction	coil
UniProt secondary structure	NA
Pos in isoform 1 [Main] CSS-Palm 4.0 PalmPred	Cys³¹⁹⁴ MC	Cys³¹⁹⁸	Cys³²¹²	Cys³²⁷¹	Cys³³⁰⁰	Cys³³⁷⁴	Cys³⁴³³	Cys³⁴⁵⁰	Cys³⁶¹³ LC	Cys³⁶³¹	Cys³⁶⁶⁵	Cys³⁷²³	Cys³⁷⁴⁸	Cys³⁹²⁰ MC
Pos in isoform 2 CSS-Palm 4.0 PalmPred	Cys³¹⁹⁸ MC	Cys³²⁰²	Cys³²¹⁶	Cys³²⁷⁵	Cys³³⁰⁴	Cys³³⁷⁸	Cys³⁴³⁷	Cys³⁴⁵⁴	Cys³⁶¹⁷ LC	Cys³⁶³⁵	Cys³⁶⁶⁹	Cys³⁷²⁷	Cys³⁷⁵²	Cys³⁹²⁴ MC
Pos in isoform 4 CSS-Palm 4.0 PalmPred
Pos in isoform 5 CSS-Palm 4.0 PalmPred
Pos in isoform 6 CSS-Palm 4.0 PalmPred

Pos in alignment	3930	3971
Subcell. location	C	C
Disulfide	no	no
PSIPRED v.4.02 prediction
UniProt secondary structure
Pos in isoform 1 [Main] CSS-Palm 4.0 PalmPred	Cys³⁹²⁶ LC	Cys³⁹⁶⁷
Pos in isoform 2 CSS-Palm 4.0 PalmPred	Cys³⁹³⁰ LC	Cys³⁹⁷¹
Pos in isoform 4 CSS-Palm 4.0 PalmPred
Pos in isoform 5 CSS-Palm 4.0 PalmPred
Pos in isoform 6 CSS-Palm 4.0 PalmPred

Legend

Subcell. location

U Undefined E Extracellular/Lumenal T Transmembrane C Cytosolic/Nuclear

Prediction confidence

Cysteine position: Predicted (high confidence prediction with CSS-Palm or/and PalmPred) and validated (in terms of disulfide bonds and cellular location) / Predicted but not validated (in terms of disulfide bond and cellular location) / Not predicted
CSS-Palm 4.0: High confidence, Medium confidence, Low confidence, Not predicted.
PalmPred: High confidence (score > 0.4), Medium confidence (0.1 < score < 0.4), Low confidence (score < 0.1), Not predicted.

Palmitoyl-proteome experiments

List of palmitoyl-proteomes

Tip: Keep CTRL key pressed down while clicking on column headers to do multiple sorting. This applies to any sortable table on this site.

ID of the experiment	Reference	Year	Organism	Cell type	Subcellular location	Technique(s)	Found?	In list	All lists
SPalmE:14	Roth AF et al.	2006	Saccharomyces cerevisiae	Isogenic LRB759	Total membrane	ABE	x		HC HC: 48 hits
SPalmE:13	Kang R et al.	2008	Rattus norvegicus	Cortical neuron	Synaptosomal membrane	ABE	x		HC: 107 hits LC: 308 hits
SPalmE:6	Martin BR et al.	2009	Homo sapiens	Jurkat	Total membrane	Click chemistry	x		HC: 127 hits LC: 188 hits List: 0 hits
SPalmE:1	Yang W et al.	2010	Homo sapiens	DU145	Total membrane	ABE	x		HC: 162 hits LC: 218 hits
SPalmE:10	Yount JS et al.	2010	Mus musculus	Dendritic cell	Total cell lysate	Click chemistry	x		HC: 59 hits LC: 105 hits
SPalmE:578	Yang W et al.	2010	Homo sapiens	DU145	Lipid raft	ABE	x		HC: 102 hits LC: 73 hits
SPalmE:577	Yang W et al.	2010	Homo sapiens	DU145	Non-lipid raft	ABE	x		HC: 63 hits LC: 147 hits
SPalmE:12	Martin BR et al.	2011	Mus musculus	BW5147-derived mouse T-cell hybridoma cell	Total membrane	Click chemistry	x		HC HC: 352 hits LC LC: 8 hits
SPalmE:2	Dowal L et al.	2011	Homo sapiens	Platelet	Total membrane	ABE	x		List: 214 hits
SPalmE:8	Merrick BA et al.	2011	Mus musculus	Macrophage Raw 264.7	Total membrane	ABE	x		List: 69 hits
SPalmE:511	Emmer BT et al.	2011	Trypanosoma brucei brucei	NA	Total cell lysate	ABE	x		List: 126 hits
SPalmE:5	Forrester MT et al.	2011	Homo sapiens	HEK293	Total membrane	ARAC	x		List: 69 hits
SPalmE:7	Wilson JP et al.	2011	Homo sapiens	Jurkat	Total cell lysate	Click chemistry	x		HC: 164 hits LC: 178 hits
SPalmE:3	Ivaldi C et al.	2012	Homo sapiens	B-cell	Total membrane	ABE	x		HC HC: 93 hits
SPalmE:580	Jones ML et al.	2012	Plasmodium falciparum	Whole organism	Total cell lysate	Click chemistry, SILAC	x		HC: 79 hits LC: 89 hits
SPalmE:162	Jones ML et al.	2012	Plasmodium falciparum	Whole organism	Total cell lysate	ABE	x		HC: 100 hits LC: 217 hits
SPalmE:11	Li Y et al.	2012	Mus musculus	Neural stem cell	Total cell lysate	Click chemistry	x		HC HC: 254 hits
SPalmE:4	Marin EP et al.	2012	Homo sapiens	Umbilical vein blood	NA	ABE	x		List: 154 hits
SPalmE:9	Ren W et al.	2013	Mus musculus	3T3-L1 and epididymal fat pads	Total membrane	ARAC	x		List: 664 hits
SPalmE:15	Hemsley PA et al.	2013	Arabidopsis thaliana	Heyn Col-4 ecotype root cell suspension	Microsomal membrane	ABE	x		HC: 122 hits MC: 94 hits LC: 366 hits
SPalmE:119	Wan J et al.	2013	Mus musculus	Brain	Total cell lysate	ABE	x		List: 378 hits
SPalmE:160	Zhang MM et al.	2013	Schizosaccharomyces pombe	Whole organism	Total cell lysate	Click chemistry	x		List: 238 hits
SPalmE:507	Chesarino NM et al.	2014	Mus musculus	DC2.4	Total cell lysate	Click chemistry	x		List: 246 hits
SPalmE:508	Chesarino NM et al.	2014	Mus musculus	MEF	Total cell lysate	Click chemistry	x		List: 436 hits
SPalmE:184	Wei X et al.	2014	Homo sapiens	HUVEC	Total cell lysate	ABE	x		Palm decreased: 40 hits Palm increased: 33 hits List: 367 hits
SPalmE:619	Peng T et al.	2015	Homo sapiens	HEK293	Total cell lysate	Alk16 Labeling	x		List: 354 hits
SPalmE:504	Serwa RA et al.	2015	Homo sapiens	RPE-1	Total cell lysate	SILAC, 16-HDYA labeling	x		List: 1348 hits
SPalmE:620	Peng T et al.	2015	Homo sapiens	HEK293	Total cell lysate	Photo cleavable x-alk16 labeling	x		List: 354 hits
SPalmE:506	Morrison E et al.	2015	Homo sapiens	Jurkat	Total cell lysate	Click chemistry, SILAC	x		List: 226 hits
SPalmE:540	Gould NS et al.	2015	Mus musculus	Liver	Total cell lysate	APE	x		List: 780 hits
SPalmE:529	Colquhoun DR et al.	2015	Homo sapiens	174 x CEM.T1	Total cell lysate	Click-IT Palmitic Acid labeling	x		List: 113 hits
SPalmE:510	Santiago-Tirado FH et al.	2015	Cryptococcus neoformans	NA	Total cell lysate	Click chemistry	x		List: 354 hits
SPalmE:509	Santiago-Tirado FH et al.	2015	Cryptococcus neoformans	NA	Total cell lysate	Click chemistry	x		List: 426 hits
SPalmE:505	Morrison E et al.	2015	Homo sapiens	Primary CD4 + T cells	Total cell lysate	ABE, In gel SILAC labeling	x		List: 274 hits
SPalmE:536	Foe IT et al.	2015	Toxoplasma gondii	NA	Total membrane	Click chemistry	x		HC: 210 hits MC: 72 hits
SPalmE:902	Caballero MC et al.	2016	Toxoplasma gondii	whole parasite lysates	NA	ABE	x		HC: 164 hits
SPalmE:829	Upadhyay S et al.	2016	Aspergillus fumigatus	Conidia	NA	ABE	x		List: 133 hits
SPalmE:724	Fang C et al.	2016	Homo sapiens	SW480	NA	ARAC	x		List: 100 hits
SPalmE:909	Thinon E et al.	2016	Mus musculus	Macrophage Raw 264.7	Total cell lysate	Alk16 Labeling	x		HC: 197 hits MC: 143 hits LC: 302 hits
SPalmE:723	Hernandez JL et al.	2016	Homo sapiens	MCF7	Total cell lysate	Alk16 Labeling	x		List: 1353 hits
SPalmE:698	Pinner AL et al.	2016	Homo sapiens	Brain	Total cell lysate	ABE	x		List: 216 hits
SPalmE:993	Shen LF et al.	2017	Mus musculus	Liver	Total membrane	ARAC	x		ZDHHC13 substrates: 16 hits
SPalmE:903	Collins MO et al.	2017	Mus musculus	Forebrain	NA	ABE	x		HC: 1079 hits
SPalmE:907	Edmonds MJ et al.	2017	Rattus norvegicus	Brain	NA	ARAC	x		List: 95 hits
SPalmE:906	Edmonds MJ et al.	2017	Rattus norvegicus	Brain	NA	ABE	x		List: 193 hits
SPalmE:855	Shen LF et al.	2017	Mus musculus	Liver	Total membrane	ARAC	x		List: 865 hits
SPalmE:1183	Thinon E et al.	2018	Homo sapiens	HeLa	Total cell lysate	NH2OH cleavage of thioester bond, Alk16 Labeling	x		HC: 132 hits MC: 138 hits LC: 110 hits
SPalmE:1184	Thinon E et al.	2018	Homo sapiens	HeLa	Total cell lysate	ARAC	Found	in LC	HC: 545 hits MC: 415 hits LC: 219 hits
SPalmE:1182	Thinon E et al.	2018	Mus musculus	Macrophage Raw 264.7	Total cell lysate	ARAC	x		HC: 198 hits MC: 143 hits LC: 120 hits
SPalmE:1186	Thinon E et al.	2018	Mus musculus	Macrophage Raw 264.7	Total cell lysate	NH2OH cleavage of thioester bond, Alk16 Labeling	x		HC: 177 hits MC: 162 hits LC: 123 hits
SPalmE:1181	Thinon E et al.	2018	Mus musculus	Macrophage Raw 264.7	Total cell lysate	NH2OH cleavage of thioester bond, Alk16 Labeling	x		HC: 244 hits MC: 187 hits LC: 120 hits
SPalmE:1191	Won SJ et al.	2018	Homo sapiens	HEK293T	Total cell lysate	Click chemistry	x		List: 195 hits
SPalmE:1192	Won SJ et al.	2018	Homo sapiens	HAP1	Total cell lysate	Click chemistry	x		List: 984 hits
SPalmE:1193	Won SJ et al.	2018	Homo sapiens	HAP1	Total cell lysate	ARAC	x		List: 1394 hits
SPalmE:1194	Won SJ et al.	2018	Homo sapiens	HAP1	Total cell lysate	ARAC,	x		List: 1404 hits
SPalmE:1203	Zhang X et al.	2018	Mus musculus	Brain	Total membrane	Enrichment by magnetic nanoparticles	x		HC: 917 hits MC: 352 hits LC: 15 hits
SPalmE:1259	Dumoulin A et al.	2018	Mus musculus	F11	Total membrane	ABE, NH2OH cleavage of thioester bond, LC-MS	x		HC: 1 hits MC: 10 hits LC: 4 hits
SPalmE:1260	Wang Z et al.	2018	Bos taurus	Lens fiber cell	Total cell lysate	ABE, NH2OH cleavage of thioester bond, LC-MS	x		List: 52 hits
SPalmE:920	Sobocińska J et al.	2018	Mus musculus	Macrophage Raw 264.7	Total cell lysate	Click chemistry	x		LPS treatment: 646 hits
SPalmE:919	Sobocińska J et al.	2018	Mus musculus	Macrophage Raw 264.7	Total cell lysate	Click chemistry	x		List: 646 hits
SPalmE:908	Sobocińska J et al.	2018	Mus musculus	Macrophage Raw 264.7	Total cell lysate	Click chemistry	x		Palm. up with LPS: 156 hits Palm. down with LPS: 189 hits
SPalmE:1185	Thinon E et al.	2018	Homo sapiens	HeLa	Total cell lysate	NH2OH cleavage of thioester bond, LC-MS, Alk16 Labeling	x		Chymotrypsin: 286 hits Trypsin: 1291 hits
SPalmE:1187	Thinon E et al.	2018	Mus musculus	Macrophage Raw 264.7	Total cell lysate	ARAC	x		HC: 281 hits MC: 139 hits LC: 113 hits
SPalmE:1303	Zaręba-Kozioł M et al.	2019	Mus musculus	Brain	Postsynaptic density fraction	ABE, NH2OH cleavage of thioester bond, LC-MS	x
SPalmE:1270	Strassburger K et al.	2019	Drosophila melanogaster	Circa 160 L2 larvae	Total cell lysate	ABE, NH2OH cleavage of thioester bond, PAT KO, MS	x		List: 13 hits
SPalmE:1266	Strassburger K et al.	2019	Drosophila melanogaster	Circa 160 L2 larvae	Total cell lysate	ABE, NH2OH cleavage of thioester bond, PAT KO, MS	x		List: 157 hits
SPalmE:1265	Wang J et al.	2019	Mus musculus	3T3-L1	Total membrane	MS, BioID	x		List: 9 hits
SPalmE:1333	Zaręba-Kozioł M et al.	2019	Mus musculus	Brain	Postsynaptic density fraction	ABE, NH2OH cleavage of thioester bond, LC-MS	x
SPalmE:1433	Zhou B et al.	2019	Homo sapiens	LNCaP	Total cell lysate	NH2OH cleavage of thioester bond, LC-MS, LB-ABE, ABE	x		List: 2929 hits
SPalmE:1432	Zhou B et al.	2019	Homo sapiens	LNCaP	Total cell lysate	ABE, SILAC, NH2OH cleavage of thioester bond, LC-MS	x		List: 590 hits
SPalmE:1434	Wegleiter T et al.	2019	Mus musculus	Neural stem cell	Total cell lysate	ABE, NH2OH cleavage of thioester bond, LC-MS	Ortholog	in List [FRAS1]	List: 370 hits
SPalmE:1438	Mariscal J et al.	2020	Homo sapiens	PC3	Total membrane	ARAC, NH2OH cleavage of thioester bond, LC-MS, LB-ABE	x		HC: 1837 hits
SPalmE:1439	Mariscal J et al.	2020	Homo sapiens	PC3	Large Extracellular Vesicles	ARAC, NH2OH cleavage of thioester bond, LC-MS, LB-ABE	x		HC: 1350 hits
SPalmE:1440	Mariscal J et al.	2020	Homo sapiens	PC3	Small Extracellular Vesicles	ARAC, NH2OH cleavage of thioester bond, LC-MS, LB-ABE	x		HC: 600 hits
SPalmE:1435	Morrison E et al.	2020	Homo sapiens	Jurkat	Total cell lysate	ABE, NH2OH cleavage of thioester bond, LC-MS, SILAC	x		Unstimulated: 37 hits
SPalmE:1436	Morrison E et al.	2020	Homo sapiens	Jurkat	Total cell lysate	ABE, NH2OH cleavage of thioester bond, LC-MS, SILAC	x		List: 185 hits
SPalmE:1458	Morrison E et al.	2020	Homo sapiens	Jurkat	Total cell lysate	ABE, NH2OH cleavage of thioester bond, LC-MS, SILAC	x		Stimulated: 148 hits
SPalmE:1437	Mariscal J et al.	2020	Homo sapiens	PC3	Total cell lysate	ARAC, NH2OH cleavage of thioester bond, LC-MS, LB-ABE	x		HC: 1869 hits
SPalmE:1450	Zaręba-Kozioł M et al.	2021	Mus musculus	Brain	Synaptoneurosomal fraction	ABE, NH2OH cleavage of thioester bond, LC-MS	x		List: 1093 hits
SPalmE:1444	Miles MR et al.	2021	Homo sapiens	Heart	Total cell lysate	ARAC, NH2OH cleavage of thioester bond, LC-MS	x		List: 687 hits
SPalmE:1447	Pradhan AJ et al.	2021	Homo sapiens	HT-29	Total cell lysate	Labeling of substrate with C20 AlkFA (Alk-18), LC-MS	Found	in List	List: 1173 hits
SPalmE:1448	Pradhan AJ et al.	2021	Homo sapiens	HT-29	Total cell lysate	Labeling of substrate with C20 AlkFA (Alk-18), LC-MS	Found	in List	List: 770 hits
SPalmE:1449	Ripamonti M et al.	2021	Mus musculus	NIH-3T3	Total cell lysate	ARAC, NH2OH cleavage of thioester bond, LC-MS	x		List: 199 hits
SPalmE:1445	Miles MR et al.	2021	Rattus norvegicus	Heart	Total cell lysate	ARAC, NH2OH cleavage of thioester bond, LC-MS	x		List: 399 hits
SPalmE:1451	Zaręba-Kozioł M et al.	2021	Mus musculus	Brain	Synaptoneurosomal fraction	ABE, NH2OH cleavage of thioester bond, LC-MS	x		List: 1048 hits
SPalmE:1452	Zaręba-Kozioł M et al.	2021	Mus musculus	Brain	Synaptoneurosomal fraction	ABE, NH2OH cleavage of thioester bond, LC-MS	x		List: 1112 hits
SPalmE:1453	Zaręba-Kozioł M et al.	2021	Mus musculus	Brain	Synaptoneurosomal fraction	ABE, NH2OH cleavage of thioester bond, LC-MS	x		List: 1040 hits
SPalmE:1455	Ziemlińska E et al.	2021	Mus musculus	Liver	Total membrane	ABE, NH2OH cleavage of thioester bond, LC-MS	x		HC: 850 hits MC: 303 hits LC: 21 hits
SPalmE:1446	Miles MR et al.	2021	Canis familiaris	Heart	Total cell lysate	ARAC, NH2OH cleavage of thioester bond, LC-MS	x		List: 464 hits
SPalmE:1454	Ziemlińska E et al.	2021	Mus musculus	Liver	Total membrane	ABE, NH2OH cleavage of thioester bond, LC-MS	x		HC: 675 hits MC: 360 hits LC: 27 hits
SPalmE:1443	Uzbekova S et al.	2021	Bos taurus	Bovine follicular cells	Total cell lysate	ABE, NH2OH cleavage of thioester bond, LC-MS	x		List: 80 hits
SPalmE:1456	Gao J et al.	2022	Mus musculus	Testis	Total cell lysate	ABE, NH2OH cleavage of thioester bond, LC-MS	x		HC: 4107 hits
SPalmE:1442	Gorenberg EL et al.	2022	Mus musculus	Brain	Total cell lysate	ARAC, NH2OH cleavage of thioester bond, LC-MS	x		List: 1597 hits
SPalmE:1441	Gorenberg EL et al.	2022	Mus musculus	Brain	Synaptic fraction	ARAC, NH2OH cleavage of thioester bond, LC-MS	x		List: 1378 hits
SPalmE:1457	Gao J et al.	2022	Mus musculus	Testis	Total cell lysate	ABE, NH2OH cleavage of thioester bond, LC-MS	x		HC: 3870 hits

Summary table by organism

Organism	Total number of palmitoyl-proteome articles	Total number of palmitoyl-proteomes	Number of palmitoyl-proteomes containing this protein or an ortholog	% of palmitoyl-proteomes containing this protein or an ortholog	Orthologs
S. cerevisiae S288c	1	1	0	0.0	NA
R. norvegicus	3	4	0	0.0	NA
H. sapiens	22	38	3	7.9	NA
M. musculus	23	37	1	2.7	FRAS1_MOUSE
T. brucei brucei	1	1	0	0.0	NA
P. falciparum	1	2	0	0.0	NA
A. thaliana	1	1	0	0.0	NA
S. pombe	1	1	0	0.0	NA
C. neoformans var. grubii serotype A strain H99	1	2	0	0.0	NA
T. gondii	2	2	0	0.0	NA
A. fumigatus	1	1	0	0.0	NA
B. taurus	2	2	0	0.0	NA
D. melanogaster	1	2	0	0.0	NA
C. familiaris	1	1	0	0.0	NA

References

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Marin EP et al.	2012	Endothelial cell palmitoylproteomic identifies novel lipid-modified targets and potential substrates for protein acyl transferases.	22496122
Li Y et al.	2012	DHHC5 protein palmitoylates flotillin-2 and is rapidly degraded on induction of neuronal differentiation in cultured cells.	22081607
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Dowal L et al.	2011	Proteomic analysis of palmitoylated platelet proteins.	21813449
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Wilson JP et al.	2011	Proteomic analysis of fatty-acylated proteins in mammalian cells with chemical reporters reveals S-acylation of histone H3 variants.	21076176
Forrester MT et al.	2011	Site-specific analysis of protein S-acylation by resin-assisted capture.	21044946
Yount JS et al.	2010	Palmitoylome profiling reveals S-palmitoylation-dependent antiviral activity of IFITM3.	20601941
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Hemsley PA et al.	2013	A proteomic approach identifies many novel palmitoylated proteins in Arabidopsis.	23252521
Ivaldi C et al.	2012	Proteomic analysis of S-acylated proteins in human B cells reveals palmitoylation of the immune regulators CD20 and CD23.	22615937
Wan J et al.	2013	Tracking brain palmitoylation change: predominance of glial change in a mouse model of Huntington's disease.	24211138
Zhang MM et al.	2013	Quantitative control of protein S-palmitoylation regulates meiotic entry in fission yeast.	23843742
Jones ML et al.	2012	Analysis of protein palmitoylation reveals a pervasive role in Plasmodium development and pathogenesis.	22901544
Wei X et al.	2014	Insulin-regulated protein palmitoylation impacts endothelial cell function.	24357059
Serwa RA et al.	2015	Systems Analysis of Protein Fatty Acylation in Herpes Simplex Virus-Infected Cells Using Chemical Proteomics.	26256475
Morrison E et al.	2015	Quantitative analysis of the human T cell palmitome.	26111759
Chesarino NM et al.	2014	Chemoproteomics reveals Toll-like receptor fatty acylation.	25371237
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Colquhoun DR et al.	2015	Bioorthogonal mimetics of palmitoyl-CoA and myristoyl-CoA and their subsequent isolation by click chemistry and characterization by mass spectrometry reveal novel acylated host-proteins modified by HIV-1 infection.	25914232
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Gould NS et al.	2015	Site-Specific Proteomic Mapping Identifies Selectively Modified Regulatory Cysteine Residues in Functionally Distinct Protein Networks.	26165157
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Pinner AL et al.	2016	Decreased protein S-palmitoylation in dorsolateral prefrontal cortex in schizophrenia.	26876311
Hernandez JL et al.	2016	Correlated S-palmitoylation profiling of Snail-induced epithelial to mesenchymal transition.	27030425
Fang C et al.	2016	Identification of Palmitoylated Transitional Endoplasmic Reticulum ATPase by Proteomic Technique and Pan Antipalmitoylation Antibody.	26865113
Caballero MC et al.	2016	Identification of new palmitoylated proteins in Toxoplasma gondii.	26825284
Upadhyay S et al.	2016	Interactions between Melanin Enzymes and Their Atypical Recruitment to the Secretory Pathway by Palmitoylation.	27879337
Edmonds MJ et al.	2017	Analysis of the brain palmitoyl-proteome using both acyl-biotin exchange and acyl-resin-assisted capture methods.	28607426
Shen LF et al.	2017	Role of S-Palmitoylation by ZDHHC13 in Mitochondrial function and Metabolism in Liver.	28526873
Sobocińska J et al.	2018	Lipopolysaccharide Upregulates Palmitoylated Enzymes of the Phosphatidylinositol Cycle: An Insight from Proteomic Studies.	29217618
Collins MO et al.	2017	Global, site-specific analysis of neuronal protein S-acylation.	28680068
Thinon E et al.	2016	Bioorthogonal Chemical Reporters for Monitoring Unsaturated Fatty-Acylated Proteins.	27350074
Thinon E et al.	2018	Selective Enrichment and Direct Analysis of Protein S-Palmitoylation Sites.	29575903
Zhang X et al.	2018	Ultradeep Palmitoylomics Enabled by Dithiodipyridine-Functionalized Magnetic Nanoparticles.	29660268
Won SJ et al.	2018	Temporal Profiling Establishes a Dynamic S-Palmitoylation Cycle.	29733200
Dumoulin A et al.	2018	S-palmitoylation Is Required for the Control of Growth Cone Morphology of DRG Neurons by CNP-Induced cGMP Signaling.	30319353
Wang Z et al.	2018	Proteomic Analysis of S-Palmitoylated Proteins in Ocular Lens Reveals Palmitoylation of AQP5 and MP20.	30489624
Wang J et al.	2019	DHHC4 and DHHC5 Facilitate Fatty Acid Uptake by Palmitoylating and Targeting CD36 to the Plasma Membrane.	30605677
Strassburger K et al.	2019	Drosophila ZDHHC8 palmitoylates scribble and Ras64B and controls growth and viability.	30735487
Zhou B et al.	2019	Low-background Acyl-biotinyl Exchange Largely Eliminates the Co-isolation of Non-S-acylated Proteins and Enables Deep S-acylproteomic Analysis.	31251020
Zaręba-Kozioł M et al.	2019	Stress-induced changes in the S-palmitoylation and S-nitrosylation of synaptic proteins.	31311849
Wegleiter T et al.	2019	Palmitoylation of BMPR1a regulates neural stem cell fate.	31772009
Morrison E et al.	2020	Dynamic palmitoylation events following T-cell receptor signaling.	32651440
Mariscal J et al.	2020	Comprehensive palmitoyl-proteomic analysis identifies distinct protein signatures for large and small cancer-derived extracellular vesicles.	32944167
Gorenberg EL et al.	2022	Identification of substrates of palmitoyl protein thioesterase 1 highlights roles of depalmitoylation in disulfide bond formation and synaptic function.	35358180
Uzbekova S et al.	2021	Protein Palmitoylation in Bovine Ovarian Follicle.	34769186
Miles MR et al.	2021	Global identification of S-palmitoylated proteins and detection of palmitoylating (DHHC) enzymes in heart.	33636221
Pradhan AJ et al.	2021	Protein acylation by saturated very long chain fatty acids and endocytosis are involved in necroptosis.	33848465
Ripamonti M et al.	2021	Structural and functional analysis of LIM domain-dependent recruitment of paxillin to αvβ3 integrin-positive focal adhesions.	33782527
Zaręba-Kozioł M et al.	2021	S-Palmitoylation of Synaptic Proteins as a Novel Mechanism Underlying Sex-Dependent Differences in Neuronal Plasticity.	34200797
Ziemlińska E et al.	2021	Palm Oil-Rich Diet Affects Murine Liver Proteome and <i>S</i>-Palmitoylome.	34884899
Gao J et al.	2022	Proteome-wide identification of palmitoylated proteins in mouse testis.	35477839