SwissPalm

Q9V3S0 CP4G1_DROME

General info Cross-references Sequences Orthologs Ortholog sequences Predictions Palmitoyl-proteomes References

Palmitoyl-proteomes

0/1 article for fruit fly
2 orthologs

Palmitoyl-proteome experiments

Validation experiments

0 experiment
0 ortholog

Curated sites & Enzymes

0 site from validation experiments^*
0 site from palmitoyl-proteomes^*
No PAT known
No APT known
^*In main isoform only

Predictions

Not predicted

Predictions

Protein general information from UniProt

Protein names

Cytochrome P450 4g1, EC 1.14.-.-; CYPIVG1

Subcellular location

Endoplasmic reticulum membrane (By similarity); Microsome membrane (By similarity)

Isoforms & protein length

Isoform 1 (main): 556 aa

Known functions

May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O. Belongs to the cytochrome P450 family. May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. Belongs to the cytochrome P450 family. May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. Belongs to the cytochrome P450 family.

Cross-references

Source	Identifiers
UniProt gene names	Cyp4g1, CG3972
UniProt secondary AC	A9UN25, Q24126, Q95U60
Refseq protein ID	NP_525031.1

Source	Identifiers
Ensembl gene	FBgn0010019

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Isoform sequence alignment

Tip: Hover over an amino acid to display its position!

Orthologs

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UniProt AC	UniProt ID	Orthology source	Organism	Gene names	Protein name	Palmitome articles	Techniques	Predicted
Q9LTL8	C71BO_ARATH	MetaPhors	A. thaliana	CYP71B24, At3g26230, MTC11.14	Cytochrome P450 71B24, EC 1.14.-.-	0/1	0	Yes
Q9FF18	C7351_ARATH	InParanoid	A. thaliana	CYP735A1, At5g38450, MXI10.18	Cytokinin hydroxylase, EC 1.14.13.-	0/1	0	No
O48786	C734A_ARATH	InParanoid	A. thaliana	CYP734A1, BAS1, At2g26710, F18A8.8	Cytochrome P450 734A1, EC 1.14.-.-	0/1	0	No
Q9LUC8	C7A13_ARATH	InParanoid	A. thaliana	CYP72A13, At3g14660, MIE1.16	Cytochrome P450 72A13, EC 1.14.-.-	0/1	0	No
Q9ZW95	C7352_ARATH	InParanoid	A. thaliana	CYP735A2, At1g67110, F5A8.3	Cytokinin hydroxylase, EC 1.14.13.-	0/1	0	Yes
Q9LUC9	C7A11_ARATH	InParanoid	A. thaliana	CYP72A11, At3g14650, MIE1.15	Cytochrome P450 72A11, EC 1.14.-.-	0/1	0	Yes
Q9LUC5	C7A15_ARATH	InParanoid	A. thaliana	CYP72A15, At3g14690, MIE1.20	Cytochrome P450 72A15, EC 1.14.-.-	0/1	0	No
Q9LUC6	C7A14_ARATH	InParanoid	A. thaliana	CYP72A14, At3g14680, MIE1.18	Cytochrome P450 72A14, EC 1.14.-.-	0/1	0	No
F4IW83	F4IW83_ARATH	InParanoid	A. thaliana	CYP72A10, ''cytochrome P450, cytochrome P450, family 72, polypeptide 10, polypeptide 10'', subfamily A, At3g14640	Cytochrome P450, family 72, subfamily A, polypeptide 10	0/1	0	No
Q9LUD3	Q9LUD3_ARATH	InParanoid	A. thaliana	''cytochrome P450, cytochrome P450, family 72, polypeptide 7, polypeptide 7'', subfamily A, At3g14610/MIE1.11, CYP72A7, At3g14610	Cytochrome P450	1/1	1	Yes
F4IW82	F4IW82_ARATH	InParanoid	A. thaliana	CYP72A9, ''cytochrome P450, cytochrome P450, family 72, polypeptide 9, polypeptide 9'', subfamily A, At3g14630	Cytochrome P450, family 72, subfamily A, polypeptide 9	0/1	0	Yes
Q9LUD2	Q9LUD2_ARATH	InParanoid	A. thaliana	CYP72A8, ''cytochrome P450, cytochrome P450, family 72, polypeptide 8, polypeptide 8'', subfamily A, At3g14620	AT3g14620/MIE1_12	0/1	0	No
Q9SHG5	C72C1_ARATH	InParanoid	A. thaliana	CYP72C1, CHI2, DLF, SHK1, SOB7, At1g17060, F20D23.24	Cytochrome P450 72C1, EC 1.14.-.-	0/1	0	No
F4IK45	C70B2_ARATH	InParanoid	A. thaliana	CYP709B2, At2g46950	Cytochrome P450 709B2, EC 1.14.-.-	0/1	0	Yes
Q9ASR3	C7091_ARATH	InParanoid	A. thaliana	CYP709B1, At2g46960	Cytochrome P450 709B1, EC 1.14.-.-	0/1	0	Yes
Q9T093	C70B3_ARATH	InParanoid	A. thaliana	CYP709B3, At4g27710	Cytochrome P450 709B3, EC 1.14.-.-	0/1	0	Yes
F4KG63	F4KG63_ARATH	InParanoid	A. thaliana	CYP715A1, ''cytochrome P450, cytochrome P450, family 715, polypeptide 1, polypeptide 1'', subfamily A, At5g52400, K24M7.14, K24M7_14	Cytochrome P450, family 715, subfamily A, polypeptide 1	0/1	0	Yes
Q93Z79	C14A1_ARATH	InParanoid	A. thaliana	CYP714A1, ELA1, At5g24910, F6A4.120	Cytochrome P450 714A1, EC 1.14.-.-	0/1	0	No
Q6NKZ8	C14A2_ARATH	InParanoid	A. thaliana	CYP714A2, ELA2, At5g24900, F6A4.110	Cytochrome P450 714A2, EC 1.14.-.-	0/1	0	Yes
O65786	C71B4_ARATH	MetaPhors	A. thaliana	CYP71B4, At3g26280, MTC11.21	Cytochrome P450 71B4, EC 1.14.-.-	0/1	0	Yes
O65787	C71B6_ARATH	MetaPhors	A. thaliana	CYP71B6, At2g24180, F27D4.9	Cytochrome P450 71B6, EC 1.14.-.-	0/1	0	Yes
Q96514	C71B7_ARATH	MetaPhors	A. thaliana	CYP71B7, At1g13110, F3F19.13	Cytochrome P450 71B7, EC 1.14.-.-	0/1	0	Yes
Q9ZU07	C71BC_ARATH	MetaPhors	A. thaliana	CYP71B12, At5g25130, F21J6.2	Cytochrome P450 71B12, EC 1.14.-.-	0/1	0	Yes
Q9LTM1	C71BM_ARATH	MetaPhors	A. thaliana	CYP71B22, At3g26200, MTC11.11	Cytochrome P450 71B22, EC 1.14.-.-	0/1	0	No
Q9LTM0	C71BN_ARATH	MetaPhors	A. thaliana	CYP71B23, At3g26210, MTC11.12	Cytochrome P450 71B23, EC 1.14.-.-	0/1	0	Yes
O64637	C76C2_ARATH	MetaPhors	A. thaliana	CYP76C2, At2g45570, F17K2.10, YLS6	Cytochrome P450 76C2, EC 1.14.-.-	0/1	0	Yes
O64638	C76C3_ARATH	MetaPhors	A. thaliana	CYP76C3, At2g45580, F17K2.11	Cytochrome P450 76C3, EC 1.14.-.-	0/1	0	No
O64635	C76C4_ARATH	MetaPhors	A. thaliana	CYP76C4, At2g45550, F17K2.8	Cytochrome P450 76C4, EC 1.14.-.-	0/1	0	Yes
O23391	O23391_ARATH	MetaPhors	A. thaliana	dl3720w, ''cytochrome P450, CYP705A2, cytochrome P450, family 705, polypeptide 2, polypeptide 2'', subfamily A, At4g15350, Dl3720W, FCAALL.274	Cytochrome P450 like protein	0/1	0	Yes
Q9LJZ2	Q9LJZ2_ARATH	MetaPhors	A. thaliana	CYP705A15, ''cytochrome P450, cytochrome P450, family 705, polypeptide 15, polypeptide 15'', subfamily A, At3g20080	Cytochrome P450, family 705, subfamily A, polypeptide 15	0/1	0	Yes
Q9LU04	Q9LU04_ARATH	MetaPhors	A. thaliana	CYP706A3, ''cytochrome P450, cytochrome P450, family 706, polypeptide 3, polypeptide 3'', subfamily A, At5g44620, K15C23.6, K15C23_6	Cytochrome P450, family 706, subfamily A, polypeptide 3	0/1	0	No
Q9SZU1	C81F4_ARATH	MetaPhors	A. thaliana	CYP81F4, At4g37410, F6G17.60	Cytochrome P450 81F4, EC 1.14.-.-	0/1	0	No
Q0WQ07	C7051_ARATH	MetaPhors	A. thaliana	dl3710c, CYP705A1, ''cytochrome P450, cytochrome P450, family 705, polypeptide 1, polypeptide 1'', subfamily A, At4g15330, Dl3710c, FCAALL.270	Cytochrome P450 705A1, EC 1.14.-.-	0/1	0	Yes
Q8GYY9	Q8GYY9_ARATH	MetaPhors	A. thaliana	CYP705A33, ''cytochrome P450, cytochrome P450, family 705, polypeptide 33, polypeptide 33'', subfamily A, At3g20960, At3g20960/MFD22_8	At3g20960	0/1	0	No
F4I6I6	F4I6I6_ARATH	MetaPhors	A. thaliana	CYP705A27, ''cytochrome P450, cytochrome P450, family 705, polypeptide 27, polypeptide 27'', subfamily A, At1g50520, F11F12.13, F11F12_13	Cytochrome P450, family 705, subfamily A, polypeptide 27	0/1	0	Yes
O22203	C98A3_ARATH	MetaPhors	A. thaliana	CYP98A3, C3'H, REF8, At2g40890, T20B5.9	Cytochrome P450 98A3, EC 1.14.-.-	0/1	0	No
O23389	O23389_ARATH	MetaPhors	A. thaliana	dl3725w, ''cytochrome P450, CYP705A3, cytochrome P450, family 705, polypeptide 3, polypeptide 3'', subfamily A, At4g15360, Dl3725W, FCAALL.277	Cytochrome P450 like protein	0/1	0	Yes
Q9CA60	C98A9_ARATH	MetaPhors	A. thaliana	CYP98A9, At1g74550, F1M20.23	Cytochrome P450 98A9, EC 1.14.-.-	0/1	0	No
Q9SW67	Q9SW67_ARATH	MetaPhors	A. thaliana	C7A10.50, ''cytochrome P450, CYP81H1, cytochrome P450, family 81, polypeptide 1, polypeptide 1'', subfamily H, At4g37310, F6G17.6	Cytochrome P450, family 81, subfamily H, polypeptide 1	0/1	0	Yes
F4IWB9	F4IWB9_ARATH	MetaPhors	A. thaliana	CYP705A28, ''cytochrome P450, cytochrome P450, family 705, MFD22.6, polypeptide 28, polypeptide 28'', subfamily A, At3g20935	Cytochrome P450, family 705, subfamily A, polypeptide 28	0/1	0	Yes
F4HRA1	F4HRA1_ARATH	MetaPhors	A. thaliana	CYP76C5, ''cytochrome P450, cytochrome P450, family 76, polypeptide 5, polypeptide 5'', subfamily C, At1g33730, F14M2.14, F14M2_14	Cytochrome P450, family 76, subfamily C, polypeptide 5	0/1	0	No
Q9SLP1	C78A9_ARATH	MetaPhors	A. thaliana	CYP78A9, At3g61880, F21F14.50	Cytochrome P450 78A9, EC 1.14.-.-	0/1	0	Yes
F4JLY4	F4JLY4_ARATH	MetaPhors	A. thaliana	CYP706A1, ''cytochrome P450, cytochrome P450, family 706, polypeptide 1, polypeptide 1'', subfamily A, At4g22690, T12H17.80, T12H17_80	Cytochrome P450, family 706, subfamily A, polypeptide 1	0/1	0	No
F4JA71	F4JA71_ARATH	MetaPhors	A. thaliana	At3g32047, F1M23.15	Cytochrome P450 superfamily protein	0/1	0	Yes
P24464	CP4AC_RAT	OrthoDB	R. norvegicus	Cyp4a12, Cyp4a-8, Cyp4a8	Cytochrome P450 4A12, EC 1.14.14.1	0/3	0	No
Q99N16	CP4F3_MOUSE	OrthoDB	M. musculus	Cyp4f3, Cyp4f18	Cytochrome P450 4F3	1/23	2	Yes
Q6ZWL3	CP4V2_HUMAN	OrthoDB	H. sapiens	CYP4V2	Cytochrome P450 4V2	0/22	0	No
Q09736	CP51_SCHPO	InParanoid	S. pombe	erg11, cyp51, SPAC13A11.02c	Lanosterol 14-alpha demethylase erg11	0/1	0	No
P54781	ERG5_YEAST	InParanoid	S. cerevisiae S288c	ERG5, CYP61, YMR015C, YM9711.02C	C-22 sterol desaturase ERG5, EC 1.14.19.41	0/1	0	Yes

Ortholog sequence alignment (CLUSTALW)

Cysteine summary and predictions

Pos in alignment	231	370	398	455	497
Subcell. location	U	U	U	U	U
Disulfide	no	no	no	no	no
PSIPRED v.4.02 prediction	helix	helix	coil	helix	helix
UniProt secondary structure	NA	NA	NA	NA	NA
Pos in isoform 1 [Main] CSS-Palm 4.0 PalmPred	Cys²³¹ MC	Cys³⁷⁰	Cys³⁹⁸	Cys⁴⁵⁵	Cys⁴⁹⁷ MC

Legend

Subcell. location

U Undefined E Extracellular/Lumenal T Transmembrane C Cytosolic/Nuclear

Prediction confidence

Cysteine position: Predicted (high confidence prediction with CSS-Palm or/and PalmPred) and validated (in terms of disulfide bonds and cellular location) / Predicted but not validated (in terms of disulfide bond and cellular location) / Not predicted
CSS-Palm 4.0: High confidence, Medium confidence, Low confidence, Not predicted.
PalmPred: High confidence (score > 0.4), Medium confidence (0.1 < score < 0.4), Low confidence (score < 0.1), Not predicted.

Palmitoyl-proteome experiments

List of palmitoyl-proteomes

Tip: Keep CTRL key pressed down while clicking on column headers to do multiple sorting. This applies to any sortable table on this site.

ID of the experiment	Reference	Year	Organism	Cell type	Subcellular location	Technique(s)	Found?	In list	All lists
SPalmE:14	Roth AF et al.	2006	Saccharomyces cerevisiae	Isogenic LRB759	Total membrane	ABE	x		HC HC: 48 hits
SPalmE:13	Kang R et al.	2008	Rattus norvegicus	Cortical neuron	Synaptosomal membrane	ABE	x		HC: 107 hits LC: 308 hits
SPalmE:6	Martin BR et al.	2009	Homo sapiens	Jurkat	Total membrane	Click chemistry	x		HC: 127 hits LC: 188 hits List: 0 hits
SPalmE:1	Yang W et al.	2010	Homo sapiens	DU145	Total membrane	ABE	x		HC: 162 hits LC: 218 hits
SPalmE:10	Yount JS et al.	2010	Mus musculus	Dendritic cell	Total cell lysate	Click chemistry	x		HC: 59 hits LC: 105 hits
SPalmE:578	Yang W et al.	2010	Homo sapiens	DU145	Lipid raft	ABE	x		HC: 102 hits LC: 73 hits
SPalmE:577	Yang W et al.	2010	Homo sapiens	DU145	Non-lipid raft	ABE	x		HC: 63 hits LC: 147 hits
SPalmE:12	Martin BR et al.	2011	Mus musculus	BW5147-derived mouse T-cell hybridoma cell	Total membrane	Click chemistry	x		HC HC: 352 hits LC LC: 8 hits
SPalmE:2	Dowal L et al.	2011	Homo sapiens	Platelet	Total membrane	ABE	x		List: 214 hits
SPalmE:8	Merrick BA et al.	2011	Mus musculus	Macrophage Raw 264.7	Total membrane	ABE	x		List: 69 hits
SPalmE:511	Emmer BT et al.	2011	Trypanosoma brucei brucei	NA	Total cell lysate	ABE	x		List: 126 hits
SPalmE:5	Forrester MT et al.	2011	Homo sapiens	HEK293	Total membrane	ARAC	x		List: 69 hits
SPalmE:7	Wilson JP et al.	2011	Homo sapiens	Jurkat	Total cell lysate	Click chemistry	x		HC: 164 hits LC: 178 hits
SPalmE:3	Ivaldi C et al.	2012	Homo sapiens	B-cell	Total membrane	ABE	x		HC HC: 93 hits
SPalmE:580	Jones ML et al.	2012	Plasmodium falciparum	Whole organism	Total cell lysate	Click chemistry, SILAC	x		HC: 79 hits LC: 89 hits
SPalmE:162	Jones ML et al.	2012	Plasmodium falciparum	Whole organism	Total cell lysate	ABE	x		HC: 100 hits LC: 217 hits
SPalmE:11	Li Y et al.	2012	Mus musculus	Neural stem cell	Total cell lysate	Click chemistry	x		HC HC: 254 hits
SPalmE:4	Marin EP et al.	2012	Homo sapiens	Umbilical vein blood	NA	ABE	x		List: 154 hits
SPalmE:9	Ren W et al.	2013	Mus musculus	3T3-L1 and epididymal fat pads	Total membrane	ARAC	x		List: 664 hits
SPalmE:15	Hemsley PA et al.	2013	Arabidopsis thaliana	Heyn Col-4 ecotype root cell suspension	Microsomal membrane	ABE	Ortholog	in LC [Q9LUD3]	HC: 122 hits MC: 94 hits LC: 366 hits
SPalmE:119	Wan J et al.	2013	Mus musculus	Brain	Total cell lysate	ABE	x		List: 378 hits
SPalmE:160	Zhang MM et al.	2013	Schizosaccharomyces pombe	Whole organism	Total cell lysate	Click chemistry	x		List: 238 hits
SPalmE:507	Chesarino NM et al.	2014	Mus musculus	DC2.4	Total cell lysate	Click chemistry	x		List: 246 hits
SPalmE:508	Chesarino NM et al.	2014	Mus musculus	MEF	Total cell lysate	Click chemistry	x		List: 436 hits
SPalmE:184	Wei X et al.	2014	Homo sapiens	HUVEC	Total cell lysate	ABE	x		Palm decreased: 40 hits Palm increased: 33 hits List: 367 hits
SPalmE:619	Peng T et al.	2015	Homo sapiens	HEK293	Total cell lysate	Alk16 Labeling	x		List: 354 hits
SPalmE:504	Serwa RA et al.	2015	Homo sapiens	RPE-1	Total cell lysate	SILAC, 16-HDYA labeling	x		List: 1348 hits
SPalmE:620	Peng T et al.	2015	Homo sapiens	HEK293	Total cell lysate	Photo cleavable x-alk16 labeling	x		List: 354 hits
SPalmE:506	Morrison E et al.	2015	Homo sapiens	Jurkat	Total cell lysate	Click chemistry, SILAC	x		List: 226 hits
SPalmE:540	Gould NS et al.	2015	Mus musculus	Liver	Total cell lysate	APE	x		List: 780 hits
SPalmE:529	Colquhoun DR et al.	2015	Homo sapiens	174 x CEM.T1	Total cell lysate	Click-IT Palmitic Acid labeling	x		List: 113 hits
SPalmE:510	Santiago-Tirado FH et al.	2015	Cryptococcus neoformans	NA	Total cell lysate	Click chemistry	x		List: 354 hits
SPalmE:509	Santiago-Tirado FH et al.	2015	Cryptococcus neoformans	NA	Total cell lysate	Click chemistry	x		List: 426 hits
SPalmE:505	Morrison E et al.	2015	Homo sapiens	Primary CD4 + T cells	Total cell lysate	ABE, In gel SILAC labeling	x		List: 274 hits
SPalmE:536	Foe IT et al.	2015	Toxoplasma gondii	NA	Total membrane	Click chemistry	x		HC: 210 hits MC: 72 hits
SPalmE:902	Caballero MC et al.	2016	Toxoplasma gondii	whole parasite lysates	NA	ABE	x		HC: 164 hits
SPalmE:829	Upadhyay S et al.	2016	Aspergillus fumigatus	Conidia	NA	ABE	x		List: 133 hits
SPalmE:724	Fang C et al.	2016	Homo sapiens	SW480	NA	ARAC	x		List: 100 hits
SPalmE:909	Thinon E et al.	2016	Mus musculus	Macrophage Raw 264.7	Total cell lysate	Alk16 Labeling	x		HC: 197 hits MC: 143 hits LC: 302 hits
SPalmE:723	Hernandez JL et al.	2016	Homo sapiens	MCF7	Total cell lysate	Alk16 Labeling	x		List: 1353 hits
SPalmE:698	Pinner AL et al.	2016	Homo sapiens	Brain	Total cell lysate	ABE	x		List: 216 hits
SPalmE:993	Shen LF et al.	2017	Mus musculus	Liver	Total membrane	ARAC	x		ZDHHC13 substrates: 16 hits
SPalmE:903	Collins MO et al.	2017	Mus musculus	Forebrain	NA	ABE	x		HC: 1079 hits
SPalmE:907	Edmonds MJ et al.	2017	Rattus norvegicus	Brain	NA	ARAC	x		List: 95 hits
SPalmE:906	Edmonds MJ et al.	2017	Rattus norvegicus	Brain	NA	ABE	x		List: 193 hits
SPalmE:855	Shen LF et al.	2017	Mus musculus	Liver	Total membrane	ARAC	x		List: 865 hits
SPalmE:1183	Thinon E et al.	2018	Homo sapiens	HeLa	Total cell lysate	NH2OH cleavage of thioester bond, Alk16 Labeling	x		HC: 132 hits MC: 138 hits LC: 110 hits
SPalmE:1184	Thinon E et al.	2018	Homo sapiens	HeLa	Total cell lysate	ARAC	x		HC: 545 hits MC: 415 hits LC: 219 hits
SPalmE:1182	Thinon E et al.	2018	Mus musculus	Macrophage Raw 264.7	Total cell lysate	ARAC	x		HC: 198 hits MC: 143 hits LC: 120 hits
SPalmE:1186	Thinon E et al.	2018	Mus musculus	Macrophage Raw 264.7	Total cell lysate	NH2OH cleavage of thioester bond, Alk16 Labeling	x		HC: 177 hits MC: 162 hits LC: 123 hits
SPalmE:1181	Thinon E et al.	2018	Mus musculus	Macrophage Raw 264.7	Total cell lysate	NH2OH cleavage of thioester bond, Alk16 Labeling	x		HC: 244 hits MC: 187 hits LC: 120 hits
SPalmE:1191	Won SJ et al.	2018	Homo sapiens	HEK293T	Total cell lysate	Click chemistry	x		List: 195 hits
SPalmE:1192	Won SJ et al.	2018	Homo sapiens	HAP1	Total cell lysate	Click chemistry	x		List: 984 hits
SPalmE:1193	Won SJ et al.	2018	Homo sapiens	HAP1	Total cell lysate	ARAC	x		List: 1394 hits
SPalmE:1194	Won SJ et al.	2018	Homo sapiens	HAP1	Total cell lysate	ARAC,	x		List: 1404 hits
SPalmE:1203	Zhang X et al.	2018	Mus musculus	Brain	Total membrane	Enrichment by magnetic nanoparticles	x		HC: 917 hits MC: 352 hits LC: 15 hits
SPalmE:1259	Dumoulin A et al.	2018	Mus musculus	F11	Total membrane	ABE, NH2OH cleavage of thioester bond, LC-MS	x		HC: 1 hits MC: 10 hits LC: 4 hits
SPalmE:1260	Wang Z et al.	2018	Bos taurus	Lens fiber cell	Total cell lysate	ABE, NH2OH cleavage of thioester bond, LC-MS	x		List: 52 hits
SPalmE:920	Sobocińska J et al.	2018	Mus musculus	Macrophage Raw 264.7	Total cell lysate	Click chemistry	x		LPS treatment: 646 hits
SPalmE:919	Sobocińska J et al.	2018	Mus musculus	Macrophage Raw 264.7	Total cell lysate	Click chemistry	x		List: 646 hits
SPalmE:908	Sobocińska J et al.	2018	Mus musculus	Macrophage Raw 264.7	Total cell lysate	Click chemistry	x		Palm. up with LPS: 156 hits Palm. down with LPS: 189 hits
SPalmE:1185	Thinon E et al.	2018	Homo sapiens	HeLa	Total cell lysate	NH2OH cleavage of thioester bond, LC-MS, Alk16 Labeling	x		Chymotrypsin: 286 hits Trypsin: 1291 hits
SPalmE:1187	Thinon E et al.	2018	Mus musculus	Macrophage Raw 264.7	Total cell lysate	ARAC	x		HC: 281 hits MC: 139 hits LC: 113 hits
SPalmE:1303	Zaręba-Kozioł M et al.	2019	Mus musculus	Brain	Postsynaptic density fraction	ABE, NH2OH cleavage of thioester bond, LC-MS	x
SPalmE:1270	Strassburger K et al.	2019	Drosophila melanogaster	Circa 160 L2 larvae	Total cell lysate	ABE, NH2OH cleavage of thioester bond, PAT KO, MS	x		List: 13 hits
SPalmE:1266	Strassburger K et al.	2019	Drosophila melanogaster	Circa 160 L2 larvae	Total cell lysate	ABE, NH2OH cleavage of thioester bond, PAT KO, MS	x		List: 157 hits
SPalmE:1265	Wang J et al.	2019	Mus musculus	3T3-L1	Total membrane	MS, BioID	x		List: 9 hits
SPalmE:1333	Zaręba-Kozioł M et al.	2019	Mus musculus	Brain	Postsynaptic density fraction	ABE, NH2OH cleavage of thioester bond, LC-MS	x
SPalmE:1433	Zhou B et al.	2019	Homo sapiens	LNCaP	Total cell lysate	NH2OH cleavage of thioester bond, LC-MS, LB-ABE, ABE	x		List: 2929 hits
SPalmE:1432	Zhou B et al.	2019	Homo sapiens	LNCaP	Total cell lysate	ABE, SILAC, NH2OH cleavage of thioester bond, LC-MS	x		List: 590 hits
SPalmE:1434	Wegleiter T et al.	2019	Mus musculus	Neural stem cell	Total cell lysate	ABE, NH2OH cleavage of thioester bond, LC-MS	x		List: 370 hits
SPalmE:1438	Mariscal J et al.	2020	Homo sapiens	PC3	Total membrane	ARAC, NH2OH cleavage of thioester bond, LC-MS, LB-ABE	x		HC: 1837 hits
SPalmE:1439	Mariscal J et al.	2020	Homo sapiens	PC3	Large Extracellular Vesicles	ARAC, NH2OH cleavage of thioester bond, LC-MS, LB-ABE	x		HC: 1350 hits
SPalmE:1440	Mariscal J et al.	2020	Homo sapiens	PC3	Small Extracellular Vesicles	ARAC, NH2OH cleavage of thioester bond, LC-MS, LB-ABE	x		HC: 600 hits
SPalmE:1435	Morrison E et al.	2020	Homo sapiens	Jurkat	Total cell lysate	ABE, NH2OH cleavage of thioester bond, LC-MS, SILAC	x		Unstimulated: 37 hits
SPalmE:1436	Morrison E et al.	2020	Homo sapiens	Jurkat	Total cell lysate	ABE, NH2OH cleavage of thioester bond, LC-MS, SILAC	x		List: 185 hits
SPalmE:1458	Morrison E et al.	2020	Homo sapiens	Jurkat	Total cell lysate	ABE, NH2OH cleavage of thioester bond, LC-MS, SILAC	x		Stimulated: 148 hits
SPalmE:1437	Mariscal J et al.	2020	Homo sapiens	PC3	Total cell lysate	ARAC, NH2OH cleavage of thioester bond, LC-MS, LB-ABE	x		HC: 1869 hits
SPalmE:1450	Zaręba-Kozioł M et al.	2021	Mus musculus	Brain	Synaptoneurosomal fraction	ABE, NH2OH cleavage of thioester bond, LC-MS	x		List: 1093 hits
SPalmE:1444	Miles MR et al.	2021	Homo sapiens	Heart	Total cell lysate	ARAC, NH2OH cleavage of thioester bond, LC-MS	x		List: 687 hits
SPalmE:1447	Pradhan AJ et al.	2021	Homo sapiens	HT-29	Total cell lysate	Labeling of substrate with C20 AlkFA (Alk-18), LC-MS	x		List: 1173 hits
SPalmE:1448	Pradhan AJ et al.	2021	Homo sapiens	HT-29	Total cell lysate	Labeling of substrate with C20 AlkFA (Alk-18), LC-MS	x		List: 770 hits
SPalmE:1449	Ripamonti M et al.	2021	Mus musculus	NIH-3T3	Total cell lysate	ARAC, NH2OH cleavage of thioester bond, LC-MS	x		List: 199 hits
SPalmE:1445	Miles MR et al.	2021	Rattus norvegicus	Heart	Total cell lysate	ARAC, NH2OH cleavage of thioester bond, LC-MS	x		List: 399 hits
SPalmE:1451	Zaręba-Kozioł M et al.	2021	Mus musculus	Brain	Synaptoneurosomal fraction	ABE, NH2OH cleavage of thioester bond, LC-MS	x		List: 1048 hits
SPalmE:1452	Zaręba-Kozioł M et al.	2021	Mus musculus	Brain	Synaptoneurosomal fraction	ABE, NH2OH cleavage of thioester bond, LC-MS	x		List: 1112 hits
SPalmE:1453	Zaręba-Kozioł M et al.	2021	Mus musculus	Brain	Synaptoneurosomal fraction	ABE, NH2OH cleavage of thioester bond, LC-MS	x		List: 1040 hits
SPalmE:1455	Ziemlińska E et al.	2021	Mus musculus	Liver	Total membrane	ABE, NH2OH cleavage of thioester bond, LC-MS	Ortholog	in MC [CP4F3]	HC: 850 hits MC: 303 hits LC: 21 hits
SPalmE:1446	Miles MR et al.	2021	Canis familiaris	Heart	Total cell lysate	ARAC, NH2OH cleavage of thioester bond, LC-MS	x		List: 464 hits
SPalmE:1454	Ziemlińska E et al.	2021	Mus musculus	Liver	Total membrane	ABE, NH2OH cleavage of thioester bond, LC-MS	x		HC: 675 hits MC: 360 hits LC: 27 hits
SPalmE:1443	Uzbekova S et al.	2021	Bos taurus	Bovine follicular cells	Total cell lysate	ABE, NH2OH cleavage of thioester bond, LC-MS	x		List: 80 hits
SPalmE:1456	Gao J et al.	2022	Mus musculus	Testis	Total cell lysate	ABE, NH2OH cleavage of thioester bond, LC-MS	x		HC: 4107 hits
SPalmE:1442	Gorenberg EL et al.	2022	Mus musculus	Brain	Total cell lysate	ARAC, NH2OH cleavage of thioester bond, LC-MS	x		List: 1597 hits
SPalmE:1441	Gorenberg EL et al.	2022	Mus musculus	Brain	Synaptic fraction	ARAC, NH2OH cleavage of thioester bond, LC-MS	x		List: 1378 hits
SPalmE:1457	Gao J et al.	2022	Mus musculus	Testis	Total cell lysate	ABE, NH2OH cleavage of thioester bond, LC-MS	x		HC: 3870 hits

Summary table by organism

Organism	Total number of palmitoyl-proteome articles	Total number of palmitoyl-proteomes	Number of palmitoyl-proteomes containing this protein or an ortholog	% of palmitoyl-proteomes containing this protein or an ortholog	Orthologs
S. cerevisiae S288c	1	1	0	0.0	NA
R. norvegicus	3	4	0	0.0	NA
H. sapiens	22	38	0	0.0	NA
M. musculus	23	37	1	2.7	CP4F3_MOUSE
T. brucei brucei	1	1	0	0.0	NA
P. falciparum	1	2	0	0.0	NA
A. thaliana	1	1	1	100.0	Q9LUD3_ARATH
S. pombe	1	1	0	0.0	NA
C. neoformans var. grubii serotype A strain H99	1	2	0	0.0	NA
T. gondii	2	2	0	0.0	NA
A. fumigatus	1	1	0	0.0	NA
B. taurus	2	2	0	0.0	NA
D. melanogaster	1	2	0	0.0	NA
C. familiaris	1	1	0	0.0	NA

References

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Pinner AL et al.	2016	Decreased protein S-palmitoylation in dorsolateral prefrontal cortex in schizophrenia.	26876311
Hernandez JL et al.	2016	Correlated S-palmitoylation profiling of Snail-induced epithelial to mesenchymal transition.	27030425
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Edmonds MJ et al.	2017	Analysis of the brain palmitoyl-proteome using both acyl-biotin exchange and acyl-resin-assisted capture methods.	28607426
Shen LF et al.	2017	Role of S-Palmitoylation by ZDHHC13 in Mitochondrial function and Metabolism in Liver.	28526873
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Collins MO et al.	2017	Global, site-specific analysis of neuronal protein S-acylation.	28680068
Thinon E et al.	2016	Bioorthogonal Chemical Reporters for Monitoring Unsaturated Fatty-Acylated Proteins.	27350074
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Zhang X et al.	2018	Ultradeep Palmitoylomics Enabled by Dithiodipyridine-Functionalized Magnetic Nanoparticles.	29660268
Won SJ et al.	2018	Temporal Profiling Establishes a Dynamic S-Palmitoylation Cycle.	29733200
Dumoulin A et al.	2018	S-palmitoylation Is Required for the Control of Growth Cone Morphology of DRG Neurons by CNP-Induced cGMP Signaling.	30319353
Wang Z et al.	2018	Proteomic Analysis of S-Palmitoylated Proteins in Ocular Lens Reveals Palmitoylation of AQP5 and MP20.	30489624
Wang J et al.	2019	DHHC4 and DHHC5 Facilitate Fatty Acid Uptake by Palmitoylating and Targeting CD36 to the Plasma Membrane.	30605677
Strassburger K et al.	2019	Drosophila ZDHHC8 palmitoylates scribble and Ras64B and controls growth and viability.	30735487
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Wegleiter T et al.	2019	Palmitoylation of BMPR1a regulates neural stem cell fate.	31772009
Morrison E et al.	2020	Dynamic palmitoylation events following T-cell receptor signaling.	32651440
Mariscal J et al.	2020	Comprehensive palmitoyl-proteomic analysis identifies distinct protein signatures for large and small cancer-derived extracellular vesicles.	32944167
Gorenberg EL et al.	2022	Identification of substrates of palmitoyl protein thioesterase 1 highlights roles of depalmitoylation in disulfide bond formation and synaptic function.	35358180
Uzbekova S et al.	2021	Protein Palmitoylation in Bovine Ovarian Follicle.	34769186
Miles MR et al.	2021	Global identification of S-palmitoylated proteins and detection of palmitoylating (DHHC) enzymes in heart.	33636221
Pradhan AJ et al.	2021	Protein acylation by saturated very long chain fatty acids and endocytosis are involved in necroptosis.	33848465
Ripamonti M et al.	2021	Structural and functional analysis of LIM domain-dependent recruitment of paxillin to αvβ3 integrin-positive focal adhesions.	33782527
Zaręba-Kozioł M et al.	2021	S-Palmitoylation of Synaptic Proteins as a Novel Mechanism Underlying Sex-Dependent Differences in Neuronal Plasticity.	34200797
Ziemlińska E et al.	2021	Palm Oil-Rich Diet Affects Murine Liver Proteome and <i>S</i>-Palmitoylome.	34884899
Gao J et al.	2022	Proteome-wide identification of palmitoylated proteins in mouse testis.	35477839